INTEGRALL

The Integron Database

Klebsiella pneumoniae
Accession Number: CP029588
Source: Sweden
Journal: Unpublished
Published: 31-MAY-2018
Title: High prevalence of unstable heteroresistance caused by gene amplification in clinical bacterial isolates
Authors: Nicoloff,H., Hjort,K., Andersson,D.I.
Remarks: Class 1 integron. In27
Promoter: PcWTGN-10
Gene Product Sequence
(216637..216772)
sensor domain-containing diguanylate cyclase (216637..216772)
(955..644)
EAL domain-containing protein (955..644)
(1031..942)
PTS fructose IIA subunit (1031..942)
(1020..1943)
IS5 family transposase (1020..1943)
(2873..2616)
hypothetical protein (2873..2616)
(3493..4929)
diguanylate cyclase (3493..4929)
(7189..5912)
DUF2254 domain-containing protein (7189..5912)
(9255..7252)
high-affinity choline transporter BetT (9255..7252)
(10098..9401)
IS1 family transposase (10098..9401)
(10170..10262)
PapC protein (10170..10262)
(11496..10289)
IS3 family transposase (11496..11175)
(11587..12071)
IS1 family transposase (11587..12071)
(12087..12629)
ISL3 family transposase (12087..12629)
silE (13356..12925)
silE silver-binding protein SilE (13356..12925)
(15082..13607)
Cu(+)/Ag(+) sensor histidine kinase (15082..13607)
(15755..15075)
DNA-binding response regulator (15755..15075)
(15945..17330)
hypothetical protein (15945..17330)
(17359..17712)
copper ABC transporter substrate-binding protein (17359..17712)
(17826..19118)
efflux RND transporter periplasmic adaptor subunit (17826..19118)
(19129..22275)
CusA/CzcA family heavy metal efflux RND transporter (19129..22275)
(22362..22802)
hypothetical protein (22362..22802)
(22929..25376)
copper-translocating P-type ATPase (22929..25376)
(25417..25614)
DUF2933 domain-containing protein (25417..25614)
(26385..25648)
peptidase M23 (26385..25648)
(27123..26674)
copper resistance protein (27123..26674)
pcoA (27357..29174)
pcoA multicopper oxidase PcoA (27357..29174)
(29174..30070)
copper resistance protein B (29174..30070)
pcoC (30110..30490)
pcoC copper resistance system chaperone PcoC (30110..30490)
(30495..31424)
copper resistance protein D (30495..31424)
(31479..32159)
DNA-binding response regulator (31479..32159)
(32156..33556)
sensor histidine kinase (32156..33556)
(33773..34207)
copper-binding protein (33773..34207)
(34618..34439)
type II toxin-antitoxin system RelE/ParE family toxin (34618..34439)
(36299..34679)
ISL3 family transposase (36299..34679)
(36361..36870)
porin (36361..36870)
(37417..36920)
N-acetyltransferase (37417..36920)
(37749..38075)
transcriptional regulator (37749..38075)
arsH (38075..38785)
arsH arsenical resistance protein ArsH (38075..38785)
(38794..39339)
RNA polymerase subunit sigma-70 (38794..39339)
(39415..39777)
arsenical resistance operon transcriptional repressor ArsD (39415..39777)
arsA (39796..41552)
arsA arsenical pump-driving ATPase (39796..41552)
(41674..42210)
N-acetyltransferase (41674..42210)
arsC (42668..42243)
arsC arsenate reductase (42668..42243)
(43970..42681)
arsenical efflux pump membrane protein ArsB (43970..42681)
arsA (45769..44018)
arsA arsenical pump-driving ATPase (45769..44018)
(46149..45787)
arsenical resistance operon transcriptional repressor ArsD (46149..45787)
(46549..46199)
transcriptional regulator (46549..46199)
(46907..47176)
hypothetical protein (46907..47176)
(47164..47739)
hypothetical protein (47164..47739)
(47770..48264)
DNA-binding protein (47770..48264)
(48308..48676)
hypothetical protein (48308..48676)
(48710..48913)
hemolysin expression modulator Hha (48710..48913)
(48962..49219)
hypothetical protein (48962..49219)
(49295..49549)
hypothetical protein (49295..49549)
(49725..49991)
DUF1778 domain-containing protein (49725..49991)
(49979..50461)
GNAT family N-acetyltransferase (49979..50461)
(50673..52019)
ISNCY family transposase (50673..52019)
(53774..52520)
IS3 family transposase (53774..52520)
(54824..53862)
Zn-dependent protease (54824..53862)
(55560..54811)
diguanylate cyclase (55560..54811)
(55748..55536)
sensor domain-containing diguanylate cyclase (55748..55536)
(55995..55798)
hypothetical protein (55995..55798)
clpK (58790..55995)
clpK heat shock survival AAA family ATPase ClpK (58790..55995)
(59474..58905)
Hsp20/alpha crystallin family protein (59474..58905)
(59790..59509)
DNA-binding protein (59790..59509)
(59986..60425)
IS66 family insertion sequence hypothetical protein (59986..60425)
(60520..60636)
hypothetical protein (60520..60636)
(60821..61518)
IS1 family transposase (60821..61518)
(61777..62757)
IS5-like element ISKpn26 family transposase (61777..62757)
(62882..62796)
ABC transporter (62882..62796)
(62934..63260)
hypothetical protein (62934..63260)
(63858..63339)
IS5-like element ISPre2 family transposase (63858..63339)
(64835..63966)
LysR family transcriptional regulator (64835..63966)
(65839..64829)
phosphonate dehydrogenase (65839..64829)
phnE (66675..65848)
phnE phosphonate ABC transporter, permease protein PhnE (66675..65848)
(67547..66684)
phosphate/phosphite/phosphonate ABC transporter substrate-binding protein (67547..66684)
phnC (68371..67544)
phnC phosphonate ABC transporter ATP-binding protein (68371..67544)
(68713..69021)
IS5/IS1182 family transposase (68713..69021)
(69931..69227)
IS6-like element IS26 family transposase (69931..69227)
(69994..71187)
Tn3 family transposase (69994..71187)
(71235..71903)
IS6 family transposase (71235..71903)
(71933..72457)
DNA resolvase (71933..72457)
(73230..72481)
hypothetical protein (73230..72481)
(73234..73626)
cysteine hydrolase (73234..73626)
(73764..74648)
EamA family transporter (73764..74648)
(75879..74680)
tetracycline efflux MFS transporter Tet(A) (75879..74680)
(75958..76635)
TetR family transcriptional regulator (75958..76635)
(76909..76667)
relaxase (76909..76667)
(78465..76951)
Tn3 family transposase (78465..76951)
(78531..79235)
IS6 family transposase IS15DIV (78531..79235)
(79729..79289)
chloramphenicol acetyltransferase CAT (79729..79289)
(80697..79867)
oxacillin-hydrolyzing class D beta-lactamase OXA-1 (80697..79867)
(81382..80828)
fluoroquinolone-acetylating aminoglycoside 6'-N-acetyltransferase AAC(6')-Ib-cr5 (81382..80828)
(82230..81526)
IS6-like element IS26 family transposase (82230..81526)
(84538..82295)
Tn3 family transposase (84538..82295)
(84552..84884)
cupin fold metalloprotein, WbuC family (84552..84884)
blaCTX-M (85806..84931)
blaCTX-M class A extended-spectrum beta-lactamase CTX-M-15 (85806..84931)
(87324..86062)
IS1380 family transposase ISEc9 (87324..86062)
(87724..87530)
hypothetical protein (87724..87530)
(87888..88445)
recombinase (87888..88445)
blaTEM (88628..89488)
blaTEM class A broad-spectrum beta-lactamase TEM-1 (88628..89488)
(92106..89635)
Tn3 family transposase (92106..89635)
(92570..92109)
DNA resolvase (92570..92109)
(93359..92595)
IS6 family transposase IS6100 (93359..92595)
(93388..93570)
resolvase (93388..93570)
(93891..93586)
PadR family transcriptional regulator (93891..93586)
(95107..93902)
chromate transporter (95107..93902)
(95466..95263)
hypothetical protein (95466..95263)
(95485..95664)
hypothetical protein (95485..95664)
(96433..95594)
sulfonamide-resistant dihydropteroate synthase Sul1 (96433..95594)
qacE (96774..96427)
qacE quaternary ammonium compound efflux SMR transporter QacE delta 1 (96774..96427)
aadA (97729..96938)
aadA ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA2 (97729..96938)
(98025..97735)
DUF1010 domain-containing protein (98025..97735)
(98634..98137)
trimethoprim-resistant dihydrofolate reductase DfrA12 (98634..98137)
(98779..99792)
class 1 integron integrase IntI1 (98779..99792)
(99731..100345)
DUF3330 domain-containing protein (99731..100345)
(100471..100623)
hypothetical protein (100471..100623)
(100598..100714)
adenine-specific DNA-methyltransferase (100598..100714)
(101364..100660)
IS6 family transposase IS15DIV (101364..100660)
(101539..101426)
DNA resolvase (101539..101426)
(101634..104531)
Tn3-like element Tn5403 family transposase (101634..104531)
(104671..104567)
hypothetical protein (104671..104567)
(105132..104668)
mRNA interferase PemK (105132..104668)
(106005..105352)
CPBP family intramembrane metalloprotease (106005..105352)
(106380..106195)
hypothetical protein (106380..106195)
(106440..106335)
replication protein (106440..106335)
(106501..106689)
hypothetical protein (106501..106689)
(106943..106686)
hypothetical protein (106943..106686)
repA (107851..106994)
repA incFII family plasmid replication initiator RepA (107851..106994)
tap (107921..107844)
tap RepA leader peptide Tap (107921..107844)
(108415..108137)
replication protein (108415..108137)
(109286..108735)
phospholipase D family protein (109286..108735)
(110279..109582)
IS1 family transposase (110279..109582)
(112561..110519)
DUF262 domain-containing protein (112561..110519)
(114005..112554)
DUF262 domain-containing protein (114005..112554)
(114338..114030)
IS3 family transposase (114338..114030)
(114594..114355)
IS110 family transposase (114594..114355)
(114778..114593)
IS1 family transposase (114778..114593)
(114833..114735)
glycosyltransferase (114833..114735)
(115620..114865)
M48 family peptidase (115620..114865)
(118901..115617)
type I restriction endonuclease subunit R (118901..115617)
(120755..118971)
cold shock domain-containing protein (120755..118971)
(121461..120778)
YecA family protein (121461..120778)
(122684..121458)
restriction endonuclease subunit S (122684..121458)
(124197..122674)
type I restriction-modification system subunit M (124197..122674)
(125198..124501)
IS1 family transposase (125198..124501)
(125977..125384)
conjugal transfer protein (125977..125384)
traX (126774..126049)
traX type-F conjugative transfer system pilin acetylase TraX (126774..126049)
traI (132077..126819)
traI conjugative transfer relaxase/helicase TraI (132077..126819)
traD (134386..132077)
traD type IV conjugative transfer system coupling protein TraD (134386..132077)
(134896..134513)
hypothetical protein (134896..134513)
(136126..135395)
complement resistance protein TraT (136126..135395)
(136979..136377)
hypothetical protein (136979..136377)
(139824..137002)
conjugal transfer protein TraG (139824..137002)
(141191..139824)
conjugal transfer protein TraH (141191..139824)
(141624..141181)
conjugal transfer protein TrbF (141624..141181)
trbB (142227..141670)
trbB type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB (142227..141670)
(142438..142199)
conjugal transfer protein TraQ (142438..142199)
traF (143201..142449)
traF type-F conjugative transfer system pilin assembly protein TraF (143201..142449)
(143548..143222)
hypothetical protein (143548..143222)
(143809..143561)
hypothetical protein (143809..143561)
(144041..143787)
conjugal transfer protein TrbE (144041..143787)
traN (146028..144073)
traN type-F conjugative transfer system mating-pair stabilization protein TraN (146028..144073)
trbC (146725..146087)
trbC type-F conjugative transfer system pilin assembly protein TrbC (146725..146087)
(147727..146738)
conjugal transfer pilus assembly protein TraU (147727..146738)
(148125..147724)
hypothetical protein (148125..147724)
traW (148795..148160)
traW type-F conjugative transfer system protein TraW (148795..148160)
trbI (149184..148795)
trbI type-F conjugative transfer system protein TrbI (149184..148795)
traC (151823..149184)
traC type IV secretion system protein TraC (151823..149184)
(152287..151895)
hypothetical protein (152287..151895)
(152560..152301)
hypothetical protein (152560..152301)
(152477..152683)
hypothetical protein (152477..152683)
(153074..152658)
hypothetical protein (153074..152658)
(153452..153141)
hypothetical protein (153452..153141)
(153671..153453)
hypothetical protein (153671..153453)
(153985..153695)
hypothetical protein (153985..153695)
(154400..153990)
hypothetical protein (154400..153990)
traV (155115..154531)
traV type IV conjugative transfer system protein TraV (155115..154531)
(155734..155162)
conjugal transfer protein TraP (155734..155162)
(157151..155727)
conjugal transfer protein TraB (157151..155727)
traK (157891..157151)
traK type-F conjugative transfer system secretin TraK (157891..157151)
traE (158444..157878)
traE type IV conjugative transfer system protein TraE (158444..157878)
traL (158769..158464)
traL type IV conjugative transfer system protein TraL (158769..158464)
traA (159151..158783)
traA type IV conjugative transfer system pilin TraA (159151..158783)
(159383..159213)
TraY domain-containing protein (159383..159213)
(160211..159552)
conjugal transfer protein TrbJ (160211..159552)
(160847..160464)
conjugal transfer protein TraM (160847..160464)
(161271..161756)
lytic transglycosylase (161271..161756)
(162118..161789)
hypothetical protein (162118..161789)
(162972..162151)
DUF945 domain-containing protein (162972..162151)
(163070..163288)
hypothetical protein (163070..163288)
(163585..163782)
hypothetical protein (163585..163782)
(163694..163909)
hypothetical protein (163694..163909)
(164218..163805)
helix-turn-helix domain-containing protein (164218..163805)
(164497..164219)
XRE family transcriptional regulator (164497..164219)
(164807..164487)
type II toxin-antitoxin system RelE/ParE family toxin (164807..164487)
(165112..164888)
hypothetical protein (165112..164888)
(165335..165123)
hypothetical protein (165335..165123)
(165723..165397)
hypothetical protein (165723..165397)
(165845..165720)
single-stranded DNA-binding protein (165845..165720)
(165829..166047)
hypothetical protein (165829..166047)
(166710..166360)
hypothetical protein (166710..166360)
(166979..166707)
hypothetical protein (166979..166707)
(167169..167654)
cytoplasmic protein (167169..167654)
(168056..167898)
type I toxin-antitoxin system hok family toxin (168056..167898)
(168253..168519)
DUF1778 domain-containing protein (168253..168519)
(168507..168998)
GNAT family N-acetyltransferase (168507..168998)
(169690..169439)
hypothetical protein (169690..169439)
(171479..169887)
IS66 family transposase (171479..169887)
(171860..171510)
IS66 family insertion sequence hypothetical protein (171860..171510)
(172297..171857)
IS66 family insertion sequence hypothetical protein (172297..171857)
(173314..172559)
DeoR/GlpR transcriptional regulator (173314..172559)
(173542..174555)
SIS domain-containing protein (173542..174555)
(174552..175463)
ROK family protein (174552..175463)
(175495..176883)
sugar porter family MFS transporter (175495..176883)
(177154..177047)
type II toxin-antitoxin system RelE/ParE family toxin (177154..177047)
(177370..178081)
IS481 family transposase (177370..178081)
(178179..178391)
hypothetical protein (178179..178391)
(179685..178522)
alpha-hydroxy-acid oxidizing protein (179685..178522)
(181008..179758)
FAD-dependent oxidoreductase (181008..179758)
(181957..181139)
ABC transporter permease (181957..181139)
(182813..181959)
ABC transporter permease (182813..181959)
(183910..182879)
ABC transporter substrate-binding protein (183910..182879)
(184250..184071)
hypothetical protein (184250..184071)
(184249..185211)
LysR family transcriptional regulator (184249..185211)
(186152..185223)
glyoxylate/hydroxypyruvate reductase A (186152..185223)
(186598..186149)
3-dehydroquinate dehydratase (186598..186149)
(187225..186611)
glutathione S-transferase family protein (187225..186611)
(188205..187222)
NAD(P)H-quinone oxidoreductase (188205..187222)
(189372..188224)
polyamine ABC transporter ATP-binding protein (189372..188224)
argE (190700..189543)
argE acetylornithine deacetylase (190700..189543)
(191390..190716)
DUF1028 domain-containing protein (191390..190716)
(191829..191395)
RidA family protein (191829..191395)
(192109..191957)
IS481 family transposase (192109..191957)
(192149..192379)
AbrB/MazE/SpoVT family DNA-binding domain-containing protein (192149..192379)
(192376..192792)
PIN domain-containing protein (192376..192792)
(193160..194083)
IS5 family transposase (193160..194083)
(194637..194263)
hypothetical protein (194637..194263)
(195019..194693)
theronine dehydrogenase (195019..194693)
(195744..195016)
plasmid SOS inhibition protein A (195744..195016)
psiB (196172..195741)
psiB conjugation system SOS inhibitor PsiB (196172..195741)
(198274..196217)
hypothetical protein (198274..196217)
(198592..198344)
DUF905 domain-containing protein (198592..198344)
(199183..198641)
single-stranded DNA-binding protein (199183..198641)
(199287..199505)
hypothetical protein (199287..199505)
(199803..200123)
hypothetical protein (199803..200123)
(200581..200018)
SAM-dependent methyltransferase (200581..200018)
(201984..200629)
DUF3560 domain-containing protein (201984..200629)
(202266..202036)
hypothetical protein (202266..202036)
(202585..202358)
hypothetical protein (202585..202358)
(202697..202895)
hypothetical protein (202697..202895)
(202810..203068)
hypothetical protein (202810..203068)
(203683..203366)
hypothetical protein (203683..203366)
(203972..203718)
DNA polymerase III subunit theta (203972..203718)
(204634..204209)
antirestriction protein (204634..204209)
(204672..204893)
hypothetical protein (204672..204893)
(205385..205155)
hypothetical protein (205385..205155)
(205600..206025)
peptidase (205600..206025)
(206025..207296)
translesion error-prone DNA polymerase V subunit UmuC (206025..207296)
(207375..207590)
plasmid stabilization protein (207375..207590)
(208811..207613)
transposase (208811..207613)
(209026..209260)
hypothetical protein (209026..209260)
(210120..209287)
hypothetical protein (210120..209287)
(211091..210120)
ParB/RepB/Spo0J family plasmid partition protein (211091..210120)
(212257..211091)
plasmid-partitioning protein SopA (212257..211091)
(213009..214019)
replication initiation protein (213009..214019)
(214553..214356)
hypothetical protein (214553..214356)
(215476..214736)
recombinase (215476..214736)