INTEGRALL

The Integron Database

Escherichia coli
Accession Number: CP029748
Source: Rectal swab - USA
Journal: Unpublished
Published: 10-JUN-2018
Title: Conjugal Transfer, Whole Genome Sequencing, and Plasmid Analysis of Four mcr-1-bearing Isolates from U.S. Patients
Authors: Zhu,W., Lawsin,A., Lindsey,R., Batra,D., Knipe,K., Yoo,B., Perry,K.A., Rowe,L.A., Lonsway,D., Limbago,B., Rasheed,J.K., Laufer-Halpin,A.
Remarks: Class 1 integron. In191
Promoter: PcH1
Gene Product Sequence
(276736..276880)
hypothetical protein (276736..276880)
(933..229)
IS6 family transposase IS15DIV (933..229)
(999..2513)
Tn3 family transposase (999..2513)
(2571..2813)
relaxase (2571..2813)
(3522..2845)
TetR family transcriptional regulator (3522..2845)
(3601..4800)
tetracycline efflux MFS transporter Tet(A) (3601..4800)
(5716..4832)
EamA family transporter (5716..4832)
(6246..5854)
cysteine hydrolase (6246..5854)
(6250..8001)
Tn3 family transposase (6250..8001)
(8059..8301)
relaxase (8059..8301)
(9010..8333)
TetR family transcriptional regulator (9010..8333)
(9089..10288)
tetracycline efflux MFS transporter Tet(A) (9089..10288)
(11204..10320)
EamA family transporter (11204..10320)
(11734..11342)
cysteine hydrolase (11734..11342)
(11741..13414)
Tn3 family transposase (11741..13414)
(14073..13369)
IS6 family transposase IS15DIV (14073..13369)
(14139..14423)
IS6 family transposase (14139..14423)
(14932..14618)
transposase (14932..14618)
(15884..14871)
integron integrase (15884..14871)
dfrA (16040..16513)
dfrA trimethoprim-resistant dihydrofolate reductase DfrA14 (16040..16513)
(16583..17287)
IS6 family transposase IS15DIV (16583..17287)
(17358..17233)
5,10-methylenetetrahydrofolate reductase (17358..17233)
(17341..17655)
recombinase family protein (17341..17655)
(17658..20624)
Tn3 family transposase (17658..20624)
(20703..21707)
IS110-like element IS5075 family transposase (20703..21707)
(22065..21889)
DUF4102 domain-containing protein (22065..21889)
(22371..22294)
transcriptional regulator (22371..22294)
(22395..23210)
sulfonamide-resistant dihydropteroate synthase Sul2 (22395..23210)
(23271..24074)
aminoglycoside O-phosphotransferase APH(3'')-Ib (23271..24074)
aph(6)-I (24074..24910)
aph(6)-I aminoglycoside O-phosphotransferase APH(6)-Id (24074..24910)
(24829..24993)
mobilization protein (MobL-like) (24829..24993)
blaTEM (26001..25141)
blaTEM class A broad-spectrum beta-lactamase TEM-1 (26001..25141)
(26741..26184)
recombinase (26741..26184)
(27066..26887)
replication initiator protein (27066..26887)
(27163..27867)
IS6 family transposase IS15DIV (27163..27867)
(27932..27813)
5,10-methylenetetrahydrofolate reductase (27932..27813)
(27961..29184)
TrhK (27961..29184)
(29186..29647)
hypothetical protein (29186..29647)
(29637..30992)
conjugal transfer protein TraB (29637..30992)
(31000..31482)
transcriptional regulator (31000..31482)
(31520..32353)
DsbC family protein (31520..32353)
(32363..33313)
TrhV (32363..33313)
(33322..36003)
conjugal transfer protein (33322..36003)
(39840..41093)
ParA family protein (39840..41093)
(41090..42094)
peptide transporter (41090..42094)
(42545..42156)
hypothetical protein (42545..42156)
(43063..42542)
hypothetical protein (43063..42542)
(43892..43056)
hypothetical protein (43892..43056)
(44836..43889)
hypothetical protein (44836..43889)
(45200..46237)
stbA family protein (45200..46237)
(46249..46887)
hypothetical protein (46249..46887)
(47291..47743)
transfer repressor (47291..47743)
(47733..48158)
htdF (47733..48158)
(48167..48721)
plasmid transfer protein (48167..48721)
(48841..53145)
hypothetical protein (48841..53145)
lepB (53423..53935)
lepB signal peptidase I (53423..53935)
(53922..55433)
conjugal transfer protein (53922..55433)
(55623..56633)
plasmid transfer protein (55623..56633)
(56652..59840)
conjugal transfer protein TraN (56652..59840)
(60741..59869)
hypothetical protein (60741..59869)
(60921..62705)
ATP-dependent helicase (60921..62705)
(63100..63972)
hypothetical protein (63100..63972)
(64030..64407)
hypothetical protein (64030..64407)
(64468..65445)
hypothetical protein (64468..65445)
(65503..66561)
ATP-binding protein (65503..66561)
(66930..68057)
DUF3150 domain-containing protein (66930..68057)
(68135..70147)
VWA domain-containing protein (68135..70147)
(70219..70440)
hypothetical protein (70219..70440)
(70554..71786)
hypothetical protein (70554..71786)
(72057..72578)
hypothetical protein (72057..72578)
(72657..73535)
hypothetical protein (72657..73535)
(73606..74541)
hypothetical protein (73606..74541)
(74610..75530)
hypothetical protein (74610..75530)
(75597..76535)
hypothetical protein (75597..76535)
(76707..77663)
hypothetical protein (76707..77663)
(77927..78202)
hypothetical protein (77927..78202)
(78247..78837)
hypothetical protein (78247..78837)
(78845..79102)
hypothetical protein (78845..79102)
(79176..79712)
hypothetical protein (79176..79712)
(79729..80175)
hypothetical protein (79729..80175)
(80248..81228)
DNA replication protein (80248..81228)
(81238..82113)
hypothetical protein (81238..82113)
(82143..83117)
IS30-like element ISApl1 family transposase (82143..83117)
mcr-1 (83313..84938)
mcr-1 phosphoethanolamine--lipid A transferase MCR-1.1 (83313..84938)
(84986..85732)
PAP2 family protein (84986..85732)
(85758..86102)
hypothetical protein (85758..86102)
(87299..86124)
recombinase (87299..86124)
(87470..87682)
hypothetical protein (87470..87682)
(88043..89125)
hypothetical protein (88043..89125)
(90791..89292)
kinase (90791..89292)
(92454..90817)
protein phosphatase 2C domain-containing protein (92454..90817)
(93494..92454)
VWA domain-containing protein (93494..92454)
(94218..93580)
VWA domain-containing protein (94218..93580)
(94859..94218)
tellurium resistance protein TerX (94859..94218)
(95520..94882)
VWA domain-containing protein (95520..94882)
(96450..95983)
tellurium resistance protein TerW (96450..95983)
(97676..96468)
DUF4236 domain-containing protein (97676..96468)
(98643..97687)
citrate lyase subunit beta (98643..97687)
(99722..98643)
hypothetical protein (99722..98643)
(100497..99724)
hypothetical protein (100497..99724)
(101632..100490)
adenine/guanine phosphoribosyltransferase (101632..100490)
(102700..101642)
carbamoyl-phosphate synthase large chain (102700..101642)
(103024..103605)
tellurium resistance protein TerZ (103024..103605)
(103605..104762)
tellurium resistance protein TerA (103605..104762)
(104785..105240)
Tellurite resistance protein TerB (104785..105240)
(105263..106303)
TerC family protein (105263..106303)
(106352..106930)
chemical-damaging agent resistance protein C (106352..106930)
(106998..107573)
TerD family protein (106998..107573)
(107604..107808)
hypothetical protein (107604..107808)
(108002..109243)
tellurium resistance protein TerF (108002..109243)
(110087..109806)
hypothetical protein (110087..109806)
(110328..110137)
hypothetical protein (110328..110137)
(110791..110420)
hypothetical protein (110791..110420)
(111134..111526)
hypothetical protein (111134..111526)
(111505..111816)
hypothetical protein (111505..111816)
(112130..112423)
XRE family transcriptional regulator (112130..112423)
(112428..113753)
type II toxin-antitoxin system HipA family toxin (112428..113753)
(113814..114020)
hypothetical protein (113814..114020)
(114122..114532)
hypothetical protein (114122..114532)
(114545..115360)
HNH endonuclease (114545..115360)
(115614..116039)
hypothetical protein (115614..116039)
(116588..116896)
hypothetical protein (116588..116896)
(116912..117769)
HNH endonuclease (116912..117769)
(117831..118079)
hypothetical protein (117831..118079)
(118784..118053)
Tn3 family transposase (118784..118053)
(119043..118618)
DUF4158 domain-containing protein (119043..118618)
(119211..119615)
resolvase (119211..119615)
(120876..119743)
permease (120876..119743)
(120982..121305)
ArsR family transcriptional regulator (120982..121305)
(121352..121450)
glycosyltransferase (121352..121450)
(121407..121783)
IS1 family transposase (121407..121783)
(121848..122552)
IS6 family transposase IS15DI (121848..122552)
(122582..123286)
RepB family plasmid replication initiator protein (122582..123286)
(123374..123640)
hypothetical protein (123374..123640)
(124863..123859)
IS110-like element IS4321 family transposase (124863..123859)
(126717..125281)
glutathione synthase (126717..125281)
(126993..126805)
hypothetical protein (126993..126805)
(126984..127688)
IS6 family transposase IS15DIV (126984..127688)
(127747..127634)
adenine-specific DNA-methyltransferase (127747..127634)
mph(A) (127810..128715)
mph(A) Mph(A) family macrolide 2'-phosphotransferase (127810..128715)
(128712..129950)
MFS transporter (128712..129950)
(129950..130534)
TetR/AcrR family transcriptional regulator (129950..130534)
(130480..130836)
hypothetical protein (130480..130836)
(130966..131055)
type VII secretion-associated protein (130966..131055)
(131791..131027)
IS6 family transposase IS6100 (131791..131027)
(131820..131939)
NTP-binding protein (131820..131939)
(132663..131959)
IS6 family transposase IS15DI (132663..131959)
(132728..132937)
IS1 family transposase (132728..132937)
(133646..132981)
hypothetical protein (133646..132981)
(134084..133704)
hypothetical protein (134084..133704)
(134727..135545)
DUF4942 domain-containing protein (134727..135545)
(135542..136747)
ATP/GTP-binding protein (135542..136747)
(137014..136811)
hypothetical protein (137014..136811)
(138346..137027)
DUF1173 family protein (138346..137027)
(140024..138597)
DNA cytosine methyltransferase (140024..138597)
(140239..140754)
thermonuclease family protein (140239..140754)
(140757..141653)
hypothetical protein (140757..141653)
(141875..142108)
hypothetical protein (141875..142108)
(142154..142408)
hypothetical protein (142154..142408)
(142446..142733)
hypothetical protein (142446..142733)
(142770..143000)
hypothetical protein (142770..143000)
(143337..143798)
hypothetical protein (143337..143798)
(143828..144235)
hypothetical protein (143828..144235)
(144603..144286)
hypothetical protein (144603..144286)
(145330..144980)
hypothetical protein (145330..144980)
(146954..145440)
Tn3 family transposase (146954..145440)
(147020..147724)
IS6 family transposase IS15DIV (147020..147724)
(147730..148476)
winged helix family transcriptional regulator (147730..148476)
(148476..148994)
hypothetical protein (148476..148994)
(149415..148999)
fosfomycin resistance glutathione transferase FosA3 (149415..148999)
(149992..149675)
IS5/IS1182 family transposase (149992..149675)
blaCTX-M (150902..150027)
blaCTX-M class A extended-spectrum beta-lactamase CTX-M-14 (150902..150027)
(151146..151259)
5,10-methylenetetrahydrofolate reductase (151146..151259)
(151909..151205)
IS6 family transposase IS15DIV (151909..151205)
aac(3) (152023..152799)
aac(3) aminoglycoside N-acetyltransferase AAC(3)-IV (152023..152799)
(152820..153041)
hypothetical protein (152820..153041)
aph(4)-Ia (153028..154053)
aph(4)-Ia aminoglycoside O-phosphotransferase APH(4)-Ia (153028..154053)
(154059..154424)
AAC(3) family N-acetyltransferase (154059..154424)
(155227..154475)
IS6 family transposase (155227..154475)
(155313..156812)
Tn3 family transposase (155313..156812)
(156848..157000)
phenol hydroxylase (156848..157000)
(157038..157523)
phenol hydroxylase (157038..157523)
(157613..157509)
class A beta-lactamase (157613..157509)
(157687..157610)
transcriptional regulator (157687..157610)
(158810..157720)
IS4 family transposase ISAba1 (158810..158270)
(158900..159715)
sulfonamide-resistant dihydropteroate synthase Sul2 (158900..159715)
(159802..160104)
phosphoglucosamine mutase (159802..160104)
(160249..159998)
hypothetical protein (160249..159998)
(161773..160280)
IS91 family transposase (161773..160280)
(162190..161885)
LysR family transcriptional regulator (162190..161885)
floR (163432..162218)
floR chloramphenicol/florfenicol efflux MFS transporter FloR (163432..162218)
(164533..163649)
DUF3363 domain-containing protein (164533..163649)
(166057..164564)
IS91 family transposase (166057..164564)
(166474..166169)
LysR family transcriptional regulator (166474..166169)
floR (167716..166502)
floR chloramphenicol/florfenicol efflux MFS transporter FloR (167716..166502)
(168817..167933)
DUF3363 domain-containing protein (168817..167933)
(169354..168848)
IS91 family transposase (169354..168848)
(169419..170123)
IS6 family transposase IS15DIV (169419..170123)
(170176..172482)
Tn3-like element Tn3 family transposase (170176..172482)
(172535..173251)
IS6-like element IS26 family transposase (172535..173251)
(173317..173862)
Tn3 family transposase (173317..173862)
(174313..173898)
IS1 family transposase (174313..173898)
(174368..174270)
glycosyltransferase (174368..174270)
(174565..174461)
hypothetical protein (174565..174461)
(175026..174562)
mRNA interferase PemK (175026..174562)
(175899..175246)
CPBP family intramembrane metalloprotease (175899..175246)
(176475..176089)
hypothetical protein (176475..176089)
repA (177695..176838)
repA incFII family plasmid replication initiator RepA (177695..176838)
(178182..177688)
hypothetical protein (178182..177688)
(178237..178163)
RepA leader peptide Tap (178237..178163)
(178316..178447)
replication protein RepA (178316..178447)
(178726..178469)
transcriptional regulator (178726..178469)
(179159..179010)
Hok/Gef family protein (179159..179010)
(179215..179424)
hypothetical protein (179215..179424)
(180052..179840)
hypothetical protein (180052..179840)
(180748..180188)
conjugal transfer protein (180748..180188)
(181711..180851)
alpha/beta hydrolase (181711..180851)
traX (182516..181770)
traX type-F conjugative transfer system pilin acetylase TraX (182516..181770)
(187806..182536)
conjugative transfer relaxase/helicase TraI (187806..182536)
(187885..188115)
antitoxin (187885..188115)
(188115..188513)
PIN domain-containing protein (188115..188513)
traD (190675..188522)
traD type IV conjugative transfer system coupling protein TraD (190675..188522)
(191662..190928)
complement resistance protein TraT (191662..190928)
(192188..191691)
entry exclusion protein (192188..191691)
(195026..192204)
conjugal transfer protein TraG (195026..192204)
(196399..195023)
conjugal transfer protein TraH (196399..195023)
(196809..196396)
conjugal transfer protein TrbF (196809..196396)
(197104..196763)
conjugal transfer protein TrbJ (197104..196763)
trbB (197579..197034)
trbB protein TrbB (197579..197034)
traQ (197850..197566)
traQ protein TraQ (197850..197566)
(197931..198245)
toxin ArtA (197931..198245)
(198594..198247)
protein TrbA (198594..198247)
traF (199383..198610)
traF type-F conjugative transfer system pilin assembly protein TraF (199383..198610)
(199606..199346)
protein TrbE (199606..199346)
(201438..199630)
type-F conjugative transfer system mating-pair stabilization protein TraN (201438..199630)
trbC (202073..201435)
trbC type-F conjugative transfer system pilin assembly protein TrbC (202073..201435)
(203074..202082)
protein TraU (203074..202082)
traW (203703..203071)
traW protein TraW (203703..203071)
trbI (204086..203700)
trbI type-F conjugative transfer system protein TrbI (204086..203700)
traC (206710..204083)
traC conjugal transfer protein TraC (206710..204083)
(207091..206870)
protein TraR (207091..206870)
traV (207741..207226)
traV type IV conjugative transfer system protein TraV (207741..207226)
(207989..207738)
protein TrbG (207989..207738)
(208231..208001)
DUF2689 domain-containing protein (208231..208001)
(208775..208185)
conjugal transfer protein TraP (208775..208185)
(210192..208765)
protein TraB (210192..208765)
traK (210863..210192)
traK type-F conjugative transfer system secretin TraK (210863..210192)
traE (211473..210907)
traE protein TraE (211473..210907)
traL (211806..211495)
traL type IV conjugative transfer system protein TraL (211806..211495)
traA (212186..211821)
traA pilin (212186..211821)
(212614..212219)
relaxosome protein TraY (212614..212219)
(213402..212713)
protein TraJ (213402..212713)
(213972..213589)
conjugal transfer protein TraM (213972..213589)
(214293..214895)
lytic transglycosylase (214293..214895)
(216088..215192)
DUF945 domain-containing protein (216088..215192)
(216419..216132)
hypothetical protein (216419..216132)
(216650..216444)
single-stranded DNA-binding protein (216650..216444)
(216840..216652)
hypothetical protein (216840..216652)
(217121..216891)
hypothetical protein (217121..216891)
(217499..217341)
protein hok (217499..217341)
(218498..217779)
plasmid SOS inhibition protein A (218498..217779)
psiB (218929..218495)
psiB conjugation system SOS inhibitor PsiB (218929..218495)
(219181..218984)
hypothetical protein (219181..218984)
(219442..219209)
DUF905 domain-containing protein (219442..219209)
(220049..219510)
single-stranded DNA-binding protein (220049..219510)
(220281..220075)
single-stranded DNA-binding protein (220281..220075)
(220492..220283)
DUF1472 domain-containing protein (220492..220283)
(220608..220426)
hypothetical protein (220608..220426)
(220792..220614)
fatty acid/phospholipid synthesis protein (220792..220614)
(222391..221420)
ParB/RepB/Spo0J family plasmid partition protein (222391..221420)
(223557..222391)
protein SopA (223557..222391)
(224554..223857)
IS1-like element IS1A family transposase (224554..223857)
(224609..224511)
glycosyltransferase (224609..224511)
(224625..224930)
hypothetical protein (224625..224930)
(227240..225039)
TonB-dependent receptor (227240..225039)
(228599..227322)
L-lysine N6-monooxygenase (228599..227322)
(230338..228596)
IucA/IucC family siderophore biosynthesis protein (230338..228596)
(231285..230338)
N-acetyltransferase (231285..230338)
(233073..231286)
aerobactin synthase IucA (233073..231286)
(233146..234339)
MFS transporter (233146..234339)
(235099..234719)
fluoride efflux transporter CrcB (235099..234719)
(235443..235171)
hypothetical protein (235443..235171)
(235853..235440)
phosphopyruvate hydratase (235853..235440)
(235851..236108)
hypothetical protein (235851..236108)
(237199..236342)
metal ABC transporter permease (237199..236342)
(238053..237196)
metal ABC transporter permease (238053..237196)
(238877..238050)
manganese/iron ABC transporter ATP-binding protein (238877..238050)
(239791..238877)
metal ABC transporter substrate-binding protein (239791..238877)
(240105..239914)
prephenate dehydratase (240105..239914)
(240086..240190)
glycosyltransferase (240086..240190)
(240147..240844)
IS1 family transposase (240147..240844)
(241537..241024)
protein ImpB (241537..241024)
(241702..241598)
AAA family ATPase (241702..241598)
(242027..241704)
helix-turn-helix domain-containing protein (242027..241704)
(242068..242364)
hypothetical protein (242068..242364)
(242773..243750)
repFIB replication protein A (242773..243750)
(244775..244035)
recombinase (244775..244035)
(245084..244896)
serine/threonine protein kinase (245084..244896)
(246366..245458)
antimicrobial resistance protein Mig-14 (246366..245458)
(247538..246429)
NAD(P)H-binding protein (247538..246429)
(247597..247881)
hypothetical protein (247597..247881)
(248924..247971)
omptin family outer membrane protease (248924..247971)
(249028..249417)
outer membrane protease (249028..249417)
(250047..249784)
hypothetical protein (250047..249784)
(250379..250197)
hypothetical protein (250379..250197)
(250539..251752)
IS3 family transposase (250539..250863)
(252168..251900)
IS3 family transposase (252168..251900)
(252167..252268)
glycosyltransferase (252167..252268)
(252225..252922)
IS1 family transposase (252225..252922)
(253136..252933)
hypothetical protein (253136..252933)
(253232..253507)
hypothetical protein (253232..253507)
(254095..253814)
hypothetical protein (254095..253814)
(254268..254435)
colicin-B (254268..254435)
(254530..254453)
colicin-B (254530..254453)
(255515..254541)
IS30-like element ISApl1 family transposase (255515..254541)
cbi (256052..255603)
cbi colicin B immunity protein (256052..255603)
(255994..256243)
hypothetical protein (255994..256243)
cma (256296..257111)
cma lipid II-degrading bacteriocin colicin M (256296..257111)
cmi (257514..257161)
cmi colicin M immunity protein (257514..257161)
(258483..257692)
phage integrase family protein (258483..257692)
(259169..258480)
hypothetical protein (259169..258480)
(259563..259213)
hypothetical protein (259563..259213)
(260108..261196)
transcriptional regulator (260108..261196)
(261198..263423)
phage T7 exclusion protein (261198..263423)
(264372..263473)
hypothetical protein (264372..263473)
(264652..264362)
hypothetical protein (264652..264362)
(264833..265006)
toxin-antitoxin system, antitoxin component, AbrB family protein (264833..265006)
(264948..265178)
AbrB/MazE/SpoVT family DNA-binding domain-containing protein (264948..265178)
(265175..265591)
PIN domain-containing protein (265175..265591)
(267891..265753)
AAA family ATPase (267891..265753)
(268245..268502)
hypothetical protein (268245..268502)
(268502..269092)
hypothetical protein (268502..269092)
(269355..270911)
chromosome segregation protein SMC (269355..270911)
(271103..271720)
proQ/FINO family protein (271103..271720)
(272118..273380)
IS1380 family transposase ISEc9 (272118..273380)
blaCTX-M (273636..274511)
blaCTX-M class A extended-spectrum beta-lactamase CTX-M-55 (273636..274511)
(274890..274558)
cupin fold metalloprotein, WbuC family (274890..274558)
(275062..274814)
hypothetical protein (275062..274814)
(276147..275068)
permease (276147..275068)
(276252..276575)
ArsR family transcriptional regulator (276252..276575)