INTEGRALL

The Integron Database

Klebsiella pneumoniae
Accession Number: CP041640
Source: Viet Nam: Ho Chi Minh
Journal: Unpublished
Published: 07-AUG-2019
Title: Coexistence of plasmid-mediated mcr-1 and blaNDM-4 genes by a clinical Klebsiella pneumoniae strain in Vietnam
Authors: Le,L., Tran,L.K., Le-Ha,T.-D., Tran,P.T.B., Le-Vo,H.-N., Nguyen,Y.-N., Nguyen,H.-L., Hoang-Ngoc,K.-Q., Matsumoto,Y., Motooka,D., Nakamura,S., Jones,J.W., Iida,T., Cao,V.
Remarks: Class 1 integron. In27
Promoter: PcWTGN-10
Gene Product Sequence
clpK (55..2850)
clpK heat shock survival AAA family ATPase ClpK (55..2850)
(2850..3047)
hypothetical protein (2850..3047)
(3097..3309)
sensor domain-containing diguanylate cyclase (3097..3309)
(3285..4034)
diguanylate cyclase (3285..4034)
(4021..4983)
M48 family metalloprotease (4021..4983)
(5071..6325)
IS3 family transposase (5071..6325)
(8172..6826)
ISNCY family transposase (8172..6826)
(8766..8368)
helix-turn-helix domain containing protein (8766..8368)
(10161..8815)
ISNCY family transposase (10161..8815)
(10851..10369)
GNAT family N-acetyltransferase (10851..10369)
(11105..10839)
DUF1778 domain-containing protein (11105..10839)
(11535..11281)
hypothetical protein (11535..11281)
(11868..11611)
hypothetical protein (11868..11611)
hha (12120..11917)
hha hemolysin expression modulator Hha (12120..11917)
(12522..12154)
hypothetical protein (12522..12154)
(13060..12566)
DNA-binding protein (13060..12566)
(13666..13091)
hypothetical protein (13666..13091)
(13923..13654)
hypothetical protein (13923..13654)
(14281..14631)
transcriptional regulator (14281..14631)
arsD (14681..15043)
arsD arsenite efflux transporter metallochaperone ArsD (14681..15043)
arsA (15061..16812)
arsA arsenite efflux transporter ATPase subunit ArsA (15061..16812)
(16860..18149)
arsenic transporter (16860..18149)
arsC (18162..18587)
arsC arsenate reductase (glutaredoxin) (18162..18587)
(19156..18620)
N-acetyltransferase (19156..18620)
arsA (21034..19278)
arsA arsenical pump-driving ATPase (21034..19278)
(21415..21053)
arsenic metallochaperone ArsD family protein (21415..21053)
(22036..21491)
sigma-70 family RNA polymerase sigma factor (22036..21491)
arsH (22755..22045)
arsH arsenical resistance protein ArsH (22755..22045)
(23081..22755)
helix-turn-helix transcriptional regulator (23081..22755)
(23413..23910)
N-acetyltransferase (23413..23910)
(24469..23960)
aquaporin (24469..23960)
(24531..26151)
ISL3 family transposase (24531..26151)
(26212..26391)
type II toxin-antitoxin system RelE/ParE family toxin (26212..26391)
pcoE (27057..26623)
pcoE copper resistance system metallochaperone PcoE (27057..26623)
pcoS (28674..27274)
pcoS copper resistance membrane spanning protein PcoS (28674..27274)
pcoR (29351..28671)
pcoR copper response regulator transcription factor PcoR (29351..28671)
pcoD (30335..29406)
pcoD copper resistance inner membrane protein PcoD (30335..29406)
pcoC (30720..30340)
pcoC copper resistance system metallochaperone PcoC (30720..30340)
pcoB (31656..30760)
pcoB copper resistance outer membrane transporter PcoB (31656..30760)
pcoA (33473..31656)
pcoA multicopper oxidase PcoA (33473..31656)
(33707..34156)
copper resistance protein (33707..34156)
(34445..35182)
peptidoglycan DD-metalloendopeptidase family protein (34445..35182)
(35413..35216)
DUF2933 domain-containing protein (35413..35216)
silP (37901..35454)
silP Ag(+)-translocating P-type ATPase SilP (37901..35454)
(38468..38028)
hypothetical protein (38468..38028)
silA (41701..38555)
silA Cu(+)/Ag(+) efflux RND transporter permease subunit SilA (41701..38555)
silB (43004..41712)
silB Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB (43004..41712)
(43471..43118)
copper ABC transporter substrate-binding protein (43471..43118)
silC (44885..43500)
silC Cu(+)/Ag(+) efflux RND transporter outer membrane channel SilC (44885..43500)
silR (45075..45755)
silR copper/silver response regulator transcription factor SilR (45075..45755)
silS (45748..47223)
silS copper/silver sensor histidine kinase SilS (45748..47223)
silE (47474..47905)
silE silver-binding protein SilE (47474..47905)
(48743..48201)
transposase (48743..48201)
(49243..48759)
IS1 family transposase (49243..48759)
(49334..50541)
IS3 family transposase (49334..49655)
(50732..51429)
IS1 family transposase (50732..51429)
(51581..53578)
BCCT family transporter (51581..53578)
(53641..54918)
DUF2254 domain-containing protein (53641..54918)
(57337..55901)
EAL domain-containing protein (57337..55901)
(57957..58214)
hypothetical protein (57957..58214)
(59810..58887)
IS5 family transposase (59810..58887)
(59799..59888)
PTS fructose IIA subunit (59799..59888)
(59875..60186)
EAL domain-containing protein (59875..60186)
(61160..60213)
sensor domain-containing diguanylate cyclase (61160..60213)
(62304..63044)
site-specific integrase (62304..63044)
(63143..63424)
hypothetical protein (63143..63424)
(64771..63761)
replication initiation protein (64771..63761)
sopA (65523..66689)
sopA plasmid-partitioning protein SopA (65523..66689)
(66689..67660)
ParB/RepB/Spo0J family plasmid partition protein (66689..67660)
(67660..68493)
hypothetical protein (67660..68493)
(68754..68520)
hypothetical protein (68754..68520)
(68969..70167)
IS200/IS605 family element transposase accessory protein TnpB (68969..70167)
(70405..70190)
type II toxin-antitoxin system Phd/YefM family antitoxin (70405..70190)
(71755..70484)
Y-family DNA polymerase (71755..70484)
umuD (72180..71755)
umuD translesion error-prone DNA polymerase V autoproteolytic subunit (72180..71755)
(72395..72625)
hypothetical protein (72395..72625)
(72849..72941)
DUF1472 domain-containing protein (72849..72941)
(73146..73571)
antirestriction protein (73146..73571)
(73808..74062)
DNA polymerase III subunit theta (73808..74062)
(74097..74414)
hypothetical protein (74097..74414)
(74970..74712)
hypothetical protein (74970..74712)
(75083..74885)
hypothetical protein (75083..74885)
(75195..75422)
hypothetical protein (75195..75422)
(75514..75744)
hypothetical protein (75514..75744)
(75796..77151)
DUF3560 domain-containing protein (75796..77151)
(77199..77762)
methyltransferase (77199..77762)
(77977..77657)
hypothetical protein (77977..77657)
(78360..78100)
hypothetical protein (78360..78100)
(78494..78275)
hypothetical protein (78494..78275)
ssb (78598..79140)
ssb single-stranded DNA-binding protein (78598..79140)
(79189..79437)
DUF905 domain-containing protein (79189..79437)
(79507..81564)
ParB/RepB/Spo0J family partition protein (79507..81564)
psiB (81609..82040)
psiB conjugation system SOS inhibitor PsiB (81609..82040)
(82037..82765)
plasmid SOS inhibition protein A (82037..82765)
(82762..83088)
theronine dehydrogenase (82762..83088)
(83144..83518)
hypothetical protein (83144..83518)
(84621..83698)
IS5 family transposase (84621..83698)
(85405..84989)
type II toxin-antitoxin system VapC family toxin (85405..84989)
(85632..85402)
AbrB/MazE/SpoVT family DNA-binding domain-containing protein (85632..85402)
(85672..85824)
IS481 family transposase (85672..85824)
(85952..86386)
RidA family protein (85952..86386)
(86391..87065)
DUF1028 domain-containing protein (86391..87065)
argE (87081..88238)
argE acetylornithine deacetylase (87081..88238)
(88409..89557)
ABC transporter ATP-binding protein (88409..89557)
(89576..90559)
NAD(P)H-quinone oxidoreductase (89576..90559)
(90556..91170)
glutathione S-transferase family protein (90556..91170)
(91183..91632)
3-dehydroquinate dehydratase (91183..91632)
(91629..92558)
glyoxylate/hydroxypyruvate reductase A (91629..92558)
(93532..92570)
LysR family transcriptional regulator (93532..92570)
(93531..93710)
hypothetical protein (93531..93710)
(93871..94902)
ABC transporter substrate-binding protein (93871..94902)
(94968..95822)
ABC transporter permease (94968..95822)
(95824..96642)
ABC transporter permease (95824..96642)
(96773..98023)
FAD-dependent oxidoreductase (96773..98023)
(98096..99259)
alpha-hydroxy-acid oxidizing protein (98096..99259)
(99602..99390)
hypothetical protein (99602..99390)
(100411..99700)
transposase family protein (100411..99700)
(100627..100734)
type II toxin-antitoxin system RelE/ParE family toxin (100627..100734)
(102286..100898)
sugar porter family MFS transporter (102286..100898)
(103229..102318)
ROK family protein (103229..102318)
(104239..103226)
SIS domain-containing protein (104239..103226)
(104467..105222)
DeoR/GlpR transcriptional regulator (104467..105222)
(105484..105924)
IS66 family insertion sequence hypothetical protein (105484..105924)
tnpB (105921..106271)
tnpB IS66 family insertion sequence element accessory protein TnpB (105921..106271)
(106302..107894)
IS66 family transposase (106302..107894)
(108091..108342)
hypothetical protein (108091..108342)
(109274..108783)
GNAT family N-acetyltransferase (109274..108783)
(109528..109262)
DUF1778 domain-containing protein (109528..109262)
(109725..109883)
type I toxin-antitoxin system Hok family toxin (109725..109883)
(110612..110127)
cytoplasmic protein (110612..110127)
(110802..111074)
hypothetical protein (110802..111074)
(111071..111421)
hypothetical protein (111071..111421)
(111952..111734)
hypothetical protein (111952..111734)
(111936..112061)
single-stranded DNA-binding protein (111936..112061)
(112058..112384)
hypothetical protein (112058..112384)
(112446..112658)
hypothetical protein (112446..112658)
(112669..112893)
hypothetical protein (112669..112893)
(112974..113293)
type II toxin-antitoxin system RelE/ParE family toxin (112974..113293)
(113283..113561)
helix-turn-helix transcriptional regulator (113283..113561)
(113562..113975)
helix-turn-helix domain-containing protein (113562..113975)
(114086..113871)
hypothetical protein (114086..113871)
(114195..113998)
hypothetical protein (114195..113998)
(114710..114492)
hypothetical protein (114710..114492)
(114808..115629)
DUF945 domain-containing protein (114808..115629)
(115677..116051)
hypothetical protein (115677..116051)
(116508..116023)
lytic transglycosylase (116508..116023)
traM (116932..117315)
traM relaxosome protein TraM (116932..117315)
(117568..118227)
conjugal transfer protein TrbJ (117568..118227)
(118396..118566)
TraY domain-containing protein (118396..118566)
traA (118628..118996)
traA type IV conjugative transfer system pilin TraA (118628..118996)
traL (119010..119315)
traL type IV conjugative transfer system protein TraL (119010..119315)
traE (119335..119901)
traE type IV conjugative transfer system protein TraE (119335..119901)
traK (119888..120628)
traK type-F conjugative transfer system secretin TraK (119888..120628)
(120628..122052)
conjugal transfer protein TraB (120628..122052)
(122045..122617)
conjugal transfer protein TraP (122045..122617)
traV (122664..123248)
traV type IV conjugative transfer system lipoprotein TraV (122664..123248)
(123379..123789)
hypothetical protein (123379..123789)
(123794..124084)
hypothetical protein (123794..124084)
(124108..124326)
hypothetical protein (124108..124326)
(124327..124637)
hypothetical protein (124327..124637)
(124704..125120)
hypothetical protein (124704..125120)
(125301..125095)
hypothetical protein (125301..125095)
(125218..125477)
hypothetical protein (125218..125477)
(125491..125883)
hypothetical protein (125491..125883)
traC (125955..128594)
traC type IV secretion system protein TraC (125955..128594)
trbI (128594..128983)
trbI type-F conjugative transfer system protein TrbI (128594..128983)
traW (128983..129648)
traW type-F conjugative transfer system protein TraW (128983..129648)
(129652..130053)
hypothetical protein (129652..130053)
(130050..131039)
conjugal transfer protein TraU (130050..131039)
trbC (131052..131690)
trbC type-F conjugative transfer system pilin assembly protein TrbC (131052..131690)
traN (131749..133704)
traN type-F conjugative transfer system mating-pair stabilization protein TraN (131749..133704)
(133736..133990)
conjugal transfer protein TrbE (133736..133990)
(133968..134216)
hypothetical protein (133968..134216)
(134229..134555)
hypothetical protein (134229..134555)
traF (134576..135328)
traF type-F conjugative transfer system pilin assembly protein TraF (134576..135328)
(135339..135578)
conjugal transfer protein TraQ (135339..135578)
trbB (135550..136107)
trbB type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB (135550..136107)
(136153..136596)
conjugal transfer protein TrbF (136153..136596)
(136586..137953)
conjugal transfer protein TraH (136586..137953)
(137953..140775)
conjugal transfer protein TraG (137953..140775)
(140798..141400)
hypothetical protein (140798..141400)
traT (141651..142382)
traT complement resistance protein TraT (141651..142382)
(142881..143264)
hypothetical protein (142881..143264)
traD (143391..145700)
traD type IV conjugative transfer system coupling protein TraD (143391..145700)
(145700..148187)
conjugative relaxase (145700..148187)
(148401..149285)
AAA family ATPase (148401..149285)
(149967..150955)
conjugal transfer protein TraI (149967..150955)
traX (151000..151725)
traX type-F conjugative transfer system pilin acetylase TraX (151000..151725)
finO (151797..152390)
finO fertility inhibition protein FinO (151797..152390)
(152576..153273)
IS1 family transposase (152576..153273)
(153577..155100)
type I restriction-modification system subunit M (153577..155100)
(155090..156316)
restriction endonuclease subunit S (155090..156316)
(156313..156996)
YecA family protein (156313..156996)
(157019..158803)
cold shock domain-containing protein (157019..158803)
(158873..162157)
type I restriction endonuclease subunit R (158873..162157)
(162154..162909)
M48 family metallopeptidase (162154..162909)
(162996..163181)
IS1 family transposase (162996..163181)
(163180..163419)
IS110 family transposase (163180..163419)
(163436..163744)
DDE-type integrase/transposase/recombinase (163436..163744)
(163769..165220)
DUF262 domain-containing protein (163769..165220)
(165213..167255)
DUF262 domain-containing protein (165213..167255)
(167495..168192)
IS1 family transposase (167495..168192)
(168488..169039)
phospholipase D family protein (168488..169039)
(169359..169637)
replication regulatory protein RepA (169359..169637)
tap (169853..169930)
tap RepA leader peptide Tap (169853..169930)
repA (169923..170780)
repA incFII family plasmid replication initiator RepA (169923..170780)
(170831..171088)
hypothetical protein (170831..171088)
(171273..171085)
hypothetical protein (171273..171085)
(171334..171439)
replication protein (171334..171439)
(171394..171579)
hypothetical protein (171394..171579)
(171769..172422)
CPBP family intramembrane metalloprotease (171769..172422)
(172515..172772)
antitoxin PemI (172515..172772)
(172774..173106)
mRNA interferase PemK (172774..173106)
(176140..173243)
Tn3-like element Tn5403 family transposase (176140..173243)
(176235..176348)
DNA resolvase (176235..176348)
(176410..177114)
IS6-like element IS26 family transposase (176410..177114)
(177173..177060)
adenine-specific DNA-methyltransferase (177173..177060)
mph(A) (177236..178141)
mph(A) Mph(A) family macrolide 2'-phosphotransferase (177236..178141)
(178138..179376)
MFS transporter (178138..179376)
(179376..179960)
TetR/AcrR family transcriptional regulator (179376..179960)
(179906..180262)
hypothetical protein (179906..180262)
(180392..180481)
type VII secretion-associated protein (180392..180481)
(181217..180453)
IS6-like element IS6100 family transposase (181217..180453)
(181246..181332)
NTP-binding protein (181246..181332)
(181398..182102)
IS6-like element IS26 family transposase (181398..182102)
(182596..182156)
CatB-related O-acetyltransferase (182596..182156)
(183564..182734)
oxacillin-hydrolyzing class D beta-lactamase OXA-1 (183564..182734)
(184249..183695)
fluoroquinolone-acetylating aminoglycoside 6'-N-acetyltransferase AAC(6')-Ib-cr5 (184249..183695)
(185097..184393)
IS6-like element IS26 family transposase (185097..184393)
(185300..186175)
class A extended-spectrum beta-lactamase CTX-M-15 (185300..186175)
(186554..186222)
cupin fold metalloprotein, WbuC family (186554..186222)
(186568..188811)
Tn3-like element Tn3 family transposase (186568..188811)
(188876..189580)
IS6-like element IS26 family transposase (188876..189580)
(191019..189757)
IS1380-like element ISEc9 family transposase (191019..189757)
(191419..191225)
DUF4158 domain-containing protein (191419..191225)
(191583..192140)
recombinase family protein (191583..192140)
(192323..193183)
class A broad-spectrum beta-lactamase TEM-1 (192323..193183)
(195801..193330)
Tn3 family transposase (195801..193330)
(196364..195804)
recombinase family protein (196364..195804)
(196840..196490)
DUF3330 domain-containing protein (196840..196490)
(197098..196841)
hypothetical protein (197098..196841)
intI1 (198056..197043)
intI1 class 1 integron integrase IntI1 (198056..197043)
dfrA12 (198201..198698)
dfrA12 trimethoprim-resistant dihydrofolate reductase DfrA12 (198201..198698)
(198810..199100)
DUF1010 domain-containing protein (198810..199100)
(199106..199897)
ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA2 (199106..199897)
(200061..200408)
quaternary ammonium compound efflux SMR transporter QacE delta 1 (200061..200408)
sul1 (200402..201241)
sul1 sulfonamide-resistant dihydropteroate synthase Sul1 (200402..201241)
(201350..201171)
hypothetical protein (201350..201171)
(201369..201572)
hypothetical protein (201369..201572)
(201638..202342)
IS6-like element IS26 family transposase (201638..202342)
(202622..202395)
hypothetical protein (202622..202395)
(202626..203018)
cysteine hydrolase (202626..203018)
(203156..204040)
EamA family transporter (203156..204040)
tet(A) (205271..204072)
tet(A) tetracycline efflux MFS transporter Tet(A) (205271..204072)
(205350..206027)
TetR family transcriptional regulator (205350..206027)
(206301..206059)
relaxase (206301..206059)
(206597..206343)
Tn3 family transposase (206597..206343)
(206663..207367)
IS6-like element IS26 family transposase (206663..207367)
(207426..207313)
adenine-specific DNA-methyltransferase (207426..207313)
(207420..207521)
resolvase (207420..207521)
(207842..207537)
helix-turn-helix transcriptional regulator (207842..207537)
chrA (209058..207853)
chrA chromate efflux transporter (209058..207853)
(209207..209326)
5,10-methylenetetrahydrofolate reductase (209207..209326)
(209976..209272)
IS6-like element IS26 family transposase (209976..209272)
(210039..211232)
Tn3 family transposase (210039..211232)
(211280..211948)
IS6 family transposase (211280..211948)
(212462..212154)
IS5/IS1182 family transposase (212462..212154)
phnC (212804..213631)
phnC phosphonate ABC transporter ATP-binding protein (212804..213631)
phnD (213628..214491)
phnD phosphate/phosphite/phosphonate ABC transporter substrate-binding protein (213628..214491)
phnE (214500..215327)
phnE phosphonate ABC transporter, permease protein PhnE (214500..215327)
(215336..216346)
phosphonate dehydrogenase (215336..216346)
(216340..217209)
LysR family transcriptional regulator (216340..217209)
(217317..217836)
IS5-like element ISPre2 family transposase (217317..217836)
(218241..217915)
hypothetical protein (218241..217915)
(219398..218418)
IS5-like element ISKpn26 family transposase (219398..218418)
(220354..219657)
IS1 family transposase (220354..219657)
(220655..220539)
transposase domain-containing protein (220655..220539)
(220863..220600)
transposase (220863..220600)
(220878..221141)
hypothetical protein (220878..221141)
(221385..221666)
helix-turn-helix domain-containing protein (221385..221666)
hsp20 (221701..222270)
hsp20 small heat shock protein sHSP20 (221701..222270)