INTEGRALL

The Integron Database

Klebsiella pneumoniae
Accession Number: CP052140
Source: blood - South Korea: Busan
Journal: Unpublished
Published: 04-MAY-2020
Title: Built-in CTX-M extended-spectrum beta-lactamase gene in Klebsiella pneumoniae ensuring stable propagation of the multidrug-resistant pathogen in clinical settings
Authors: Yoon,E.-J., Gwon,B., Liu,C., Kim,D., Won,D., Park,S.G., Choi,J.R., Jeong,S.H.
Remarks: Class 1 integron In191
Promoter: PcH1
Gene Product Sequence
(1..1011)
replication initiation protein (1..1011)
(2469..1729)
site-specific integrase (2469..1729)
(3613..4560)
sensor domain-containing diguanylate cyclase (3613..4560)
(4898..4587)
EAL domain-containing protein (4898..4587)
(4918..5886)
IS5 family transposase (4918..5886)
(6816..6559)
hypothetical protein (6816..6559)
(7436..8872)
EAL domain-containing protein (7436..8872)
(11132..9855)
DUF2254 domain-containing protein (11132..9855)
betT (13192..11195)
betT choline BCCT transporter BetT (13192..11195)
(14041..13344)
IS1 family transposase (14041..13344)
(15439..14232)
IS3 family transposase (15439..15118)
(15530..16014)
IS1 family transposase (15530..16014)
(16030..16572)
ISL3 family transposase (16030..16572)
silE (17299..16868)
silE silver-binding protein SilE (17299..16868)
silS (19025..17550)
silS copper/silver sensor histidine kinase SilS (19025..17550)
silR (19698..19018)
silR copper/silver response regulator transcription factor SilR (19698..19018)
silC (19888..21273)
silC Cu(+)/Ag(+) efflux RND transporter outer membrane channel SilC (19888..21273)
cusF (21302..21655)
cusF cation efflux system protein CusF (21302..21655)
silB (21769..23061)
silB Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB (21769..23061)
silA (23072..26218)
silA Cu(+)/Ag(+) efflux RND transporter permease subunit SilA (23072..26218)
(26305..26745)
hypothetical protein (26305..26745)
silP (26872..29325)
silP Ag(+)-translocating P-type ATPase SilP (26872..29325)
(29366..29563)
DUF2933 domain-containing protein (29366..29563)
(30334..29597)
peptidoglycan DD-metalloendopeptidase family protein (30334..29597)
(31072..30623)
copper resistance protein (31072..30623)
pcoA (31306..33123)
pcoA multicopper oxidase PcoA (31306..33123)
pcoB (33123..34019)
pcoB copper resistance outer membrane transporter PcoB (33123..34019)
pcoC (34059..34439)
pcoC copper resistance system metallochaperone PcoC (34059..34439)
pcoD (34444..35373)
pcoD copper resistance inner membrane protein PcoD (34444..35373)
pcoR (35428..36108)
pcoR copper response regulator transcription factor PcoR (35428..36108)
pcoS (36105..37505)
pcoS copper resistance membrane spanning protein PcoS (36105..37505)
pcoE (37722..38156)
pcoE copper resistance system metallochaperone PcoE (37722..38156)
(38567..38388)
type II toxin-antitoxin system RelE/ParE family toxin (38567..38388)
(40248..38628)
ISL3 family transposase (40248..38628)
(40310..40819)
porin (40310..40819)
(41366..40869)
N-acetyltransferase (41366..40869)
(41698..42024)
helix-turn-helix transcriptional regulator (41698..42024)
arsH (42021..42734)
arsH arsenical resistance protein ArsH (42021..42734)
(42743..43288)
sigma-70 family RNA polymerase sigma factor (42743..43288)
(43364..43726)
arsenic metallochaperone ArsD family protein (43364..43726)
arsA (43751..45501)
arsA arsenical pump-driving ATPase (43751..45501)
(45623..46159)
N-acetyltransferase (45623..46159)
arsC (46617..46192)
arsC glutaredoxin-dependent arsenate reductase (46617..46192)
arsB (47919..46630)
arsB arsenite efflux transporter membrane subunit ArsB (47919..46630)
arsA (49718..47967)
arsA arsenite efflux transporter ATPase subunit ArsA (49718..47967)
arsD (50098..49736)
arsD arsenite efflux transporter metallochaperone ArsD (50098..49736)
arsR (50498..50148)
arsR As(III)-sensing metalloregulatory transcriptional repressor ArsR (50498..50148)
(50856..51125)
hypothetical protein (50856..51125)
(51113..51688)
hypothetical protein (51113..51688)
(51719..52213)
DNA-binding protein (51719..52213)
(52257..52625)
hypothetical protein (52257..52625)
hha (52659..52862)
hha hemolysin expression modulator Hha (52659..52862)
(52911..53168)
hypothetical protein (52911..53168)
(53244..53498)
hypothetical protein (53244..53498)
(53674..53940)
DUF1778 domain-containing protein (53674..53940)
(53928..54410)
GNAT family N-acetyltransferase (53928..54410)
(54618..55964)
ISNCY family transposase (54618..55964)
(56013..56408)
helix-turn-helix domain containing protein (56013..56408)
(57810..56556)
IS3 family transposase (57810..56556)
(58860..57898)
M48 family metalloprotease (58860..57898)
(59596..58847)
diguanylate cyclase (59596..58847)
(60031..59834)
hypothetical protein (60031..59834)
clpK (62826..60031)
clpK heat shock survival AAA family ATPase ClpK (62826..60031)
hsp20 (63519..62950)
hsp20 small heat shock protein sHSP20 (63519..62950)
(63835..63554)
helix-turn-helix domain-containing protein (63835..63554)
(64342..64079)
hypothetical protein (64342..64079)
(64357..64620)
transposase (64357..64620)
(64565..64681)
transposase domain-containing protein (64565..64681)
(64866..65563)
IS1 family transposase (64866..65563)
(66778..65771)
formamidase (66778..65771)
urtE (67503..66814)
urtE urea ABC transporter ATP-binding subunit UrtE (67503..66814)
urtD (68263..67514)
urtD urea ABC transporter ATP-binding protein UrtD (68263..67514)
urtC (69375..68260)
urtC urea ABC transporter permease subunit UrtC (69375..68260)
urtB (70311..69385)
urtB urea ABC transporter permease subunit UrtB (70311..69385)
urtA (71558..70368)
urtA urea ABC transporter substrate-binding protein (71558..70368)
(71863..75243)
response regulator (71863..75243)
(75206..76126)
response regulator transcription factor (75206..76126)
(76178..76642)
IS91 family transposase (76178..76642)
(77066..76686)
transposase family protein (77066..76686)
(78091..77123)
IS5 family transposase (78091..77123)
(78365..79369)
IS110-like element IS5075 family transposase (78365..79369)
(79727..79551)
DUF4102 domain-containing protein (79727..79551)
(80033..79956)
transcriptional regulator (80033..79956)
sul2 (80057..80872)
sul2 sulfonamide-resistant dihydropteroate synthase Sul2 (80057..80872)
aph(3'')-Ib (80933..81736)
aph(3'')-Ib aminoglycoside O-phosphotransferase APH(3'')-Ib (80933..81736)
(81736..82572)
aminoglycoside O-phosphotransferase APH(6)-Id (81736..82572)
(83083..82544)
IS91 family transposase (83083..82544)
(84153..83293)
class A broad-spectrum beta-lactamase TEM-1 (84153..83293)
(84893..84336)
recombinase family protein (84893..84336)
(85057..85251)
DUF4158 domain-containing protein (85057..85251)
(85457..86719)
IS1380-like element ISEc9 family transposase (85457..86719)
(86975..87850)
class A extended-spectrum beta-lactamase CTX-M-15 (86975..87850)
(88229..87897)
cupin fold metalloprotein, WbuC family (88229..87897)
(88243..91038)
Tn3-like element Tn3 family transposase (88243..91038)
(91108..91812)
IS6-like element IS26 family transposase (91108..91812)
(92032..91847)
IS1 family transposase (92032..91847)
(92161..93564)
DNA cytosine methyltransferase (92161..93564)
(94812..93598)
type II site-specific deoxyribonuclease (94812..93598)
(94868..94933)
EAL domain-containing protein (94868..94933)
(95837..95073)
IS6-like element IS6100 family transposase (95837..95073)
mobC (96246..95980)
mobC plasmid mobilization relaxosome protein MobC (96246..95980)
(96940..96467)
trimethoprim-resistant dihydrofolate reductase DfrA14 (96940..96467)
intI1 (97096..98109)
intI1 class 1 integron integrase IntI1 (97096..98109)
(98655..99359)
IS6-like element IS26 family transposase (98655..99359)
(99409..100140)
SDR family oxidoreductase (99409..100140)
(100876..100232)
quinolone resistance pentapeptide repeat protein QnrB1 (100876..100232)
pspF (101371..100970)
pspF phage shock protein operon transcriptional activator (101371..100970)
(103249..101447)
Tn3-like element IS3000 family transposase (103249..101447)
(106181..103284)
Tn3-like element Tn5403 family transposase (106181..103284)
(106276..106881)
recombinase family protein (106276..106881)
(107417..106905)
Tn3 family transposase (107417..106905)
(107483..108187)
IS6-like element IS26 family transposase (107483..108187)
(108732..108133)
hypothetical protein (108732..108133)
(110111..108732)
conjugal transfer protein TraH (110111..108732)
trbF (110532..110089)
trbF F-type conjugal transfer protein TrbF (110532..110089)
trbB (111135..110578)
trbB type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB (111135..110578)
traQ (111346..111107)
traQ type-F conjugative transfer system pilin chaperone TraQ (111346..111107)
traF (112109..111357)
traF type-F conjugative transfer system pilin assembly protein TraF (112109..111357)
(112456..112130)
hypothetical protein (112456..112130)
(112717..112469)
hypothetical protein (112717..112469)
trbE (112949..112695)
trbE conjugal transfer protein TrbE (112949..112695)
traN (114936..112981)
traN type-F conjugative transfer system mating-pair stabilization protein TraN (114936..112981)
trbC (115642..114995)
trbC type-F conjugative transfer system pilin assembly protein TrbC (115642..114995)
(115897..115721)
hypothetical protein (115897..115721)
traU (116907..115918)
traU conjugal transfer pilus assembly protein TraU (116907..115918)
(117305..116904)
hypothetical protein (117305..116904)
traW (117975..117340)
traW type-F conjugative transfer system protein TraW (117975..117340)
trbI (118364..117975)
trbI type-F conjugative transfer system protein TrbI (118364..117975)
traC (121003..118364)
traC type IV secretion system protein TraC (121003..118364)
(121473..121075)
hypothetical protein (121473..121075)
(121627..121481)
hypothetical protein (121627..121481)
(121658..121926)
hypothetical protein (121658..121926)
(122317..121913)
hypothetical protein (122317..121913)
(122695..122384)
hypothetical protein (122695..122384)
(122914..122696)
hypothetical protein (122914..122696)
(123227..122938)
hypothetical protein (123227..122938)
(123642..123232)
hypothetical protein (123642..123232)
traV (124358..123774)
traV type IV conjugative transfer system lipoprotein TraV (124358..123774)
traP (124977..124381)
traP conjugal transfer protein TraP (124977..124381)
(126394..124970)
conjugal transfer protein TraB (126394..124970)
traK (127134..126394)
traK type-F conjugative transfer system secretin TraK (127134..126394)
traE (127687..127121)
traE type IV conjugative transfer system protein TraE (127687..127121)
traL (128012..127707)
traL type IV conjugative transfer system protein TraL (128012..127707)
traA (128394..128026)
traA type IV conjugative transfer system pilin TraA (128394..128026)
(128626..128456)
TraY domain-containing protein (128626..128456)
(129145..128795)
conjugal transfer protein TrbJ (129145..128795)
ltrA (130691..129204)
ltrA group II intron reverse transcriptase/maturase (130691..129204)
(131423..131055)
conjugal transfer protein TrbJ (131423..131055)
traM (132039..131623)
traM relaxosome protein TraM (132039..131623)
(132430..132915)
transglycosylase SLT domain-containing protein (132430..132915)
(133277..132948)
hypothetical protein (133277..132948)
(134131..133310)
DUF945 domain-containing protein (134131..133310)
(134582..134241)
hypothetical protein (134582..134241)
(135522..134959)
methyltransferase (135522..134959)
(136925..135570)
DUF3560 domain-containing protein (136925..135570)
(137207..136977)
hypothetical protein (137207..136977)
(137526..137299)
hypothetical protein (137526..137299)
(137673..137545)
single-stranded DNA-binding protein (137673..137545)
(137945..137769)
hypothetical protein (137945..137769)
(138570..138253)
hypothetical protein (138570..138253)
(138859..138605)
DNA polymerase III subunit theta (138859..138605)
(139521..139096)
antirestriction protein (139521..139096)
(140271..140041)
hypothetical protein (140271..140041)
ltrA (142016..140505)
ltrA group II intron reverse transcriptase/maturase (142016..140505)
umuD (142418..142843)
umuD translesion error-prone DNA polymerase V autoproteolytic subunit (142418..142843)
(142843..144114)
Y-family DNA polymerase (142843..144114)
(144193..144444)
type II toxin-antitoxin system Phd/YefM family antitoxin (144193..144444)
(146641..144689)
DUF262 domain-containing protein (146641..144689)
(147918..146638)
DUF262 domain-containing protein (147918..146638)
(148829..148428)
hypothetical protein (148829..148428)
(148886..149583)
IS1 family transposase (148886..149583)
(151477..150358)
IS3 family transposase (151477..150358)
(153491..152520)
ParB/RepB/Spo0J family plasmid partition protein (153491..152520)
sopA (154657..153491)
sopA plasmid-partitioning protein SopA (154657..153491)