INTEGRALL

The Integron Database

Klebsiella pneumoniae subsp. pneumoniae
Accession Number: CP023488
Source: South Africa: Durban
Journal: Unpublished
Published: 24-OCT-2017
Title: NDM-1 encoding plasmid
Authors: Pedersen,T., Osei Sekyere,J., Sivertsen,A., Samuelsen,O., Essack,S., Sundsfjord,A.
Remarks: Class 1 integron. In191
Promoter: PcH1
Gene Product Sequence
traN (48..1)
traN type-F conjugative transfer system mating-pair stabilization protein TraN (48..1)
trbC (745..107)
trbC type-F conjugative transfer system pilin assembly protein TrbC (745..107)
(1746..758)
conjugal transfer protein TraU (1746..758)
(2144..1743)
hypothetical protein (2144..1743)
traW (2814..2179)
traW type-F conjugative transfer system protein TraW (2814..2179)
trbI (3203..2814)
trbI type-F conjugative transfer system protein TrbI (3203..2814)
traC (5842..3200)
traC type-IV secretion system protein TraC (5842..3200)
(6306..5914)
hypothetical protein (6306..5914)
(6580..6320)
hypothetical protein (6580..6320)
(6497..6703)
hypothetical protein (6497..6703)
(7094..6690)
hypothetical protein (7094..6690)
(7472..7161)
hypothetical protein (7472..7161)
(7691..7473)
hypothetical protein (7691..7473)
(8207..7797)
hypothetical protein (8207..7797)
traV (8923..8339)
traV type IV conjugative transfer system protein TraV (8923..8339)
(10461..9037)
conjugal transfer protein TraB (10461..9037)
traK (11201..10461)
traK type-F conjugative transfer system secretin TraK (11201..10461)
traE (11754..11188)
traE type IV conjugative transfer system protein TraE (11754..11188)
traL (12079..11774)
traL type IV conjugative transfer system protein TraL (12079..11774)
traA (12461..12093)
traA type IV conjugative transfer system pilin TraA (12461..12093)
(12730..12530)
TraY domain-containing protein (12730..12530)
(13518..12814)
hypothetical protein (13518..12814)
(14148..13756)
conjugal transfer protein TraM (14148..13756)
(14580..15065)
lytic transglycosylase (14580..15065)
(15427..15098)
hypothetical protein (15427..15098)
(16281..15460)
DUF945 domain-containing protein (16281..15460)
(16378..16597)
hypothetical protein (16378..16597)
(16512..16772)
hypothetical protein (16512..16772)
(17496..17097)
hypothetical protein (17496..17097)
(21014..17652)
type III restriction endonuclease subunit R (21014..17652)
(24154..21014)
site-specific DNA-methyltransferase (24154..21014)
(27172..24209)
ATP-dependent helicase (27172..24209)
(27404..27159)
XRE family transcriptional regulator (27404..27159)
(27672..28819)
IS3 family transposase (27672..27909)
(28835..29008)
IS481 family transposase (28835..29008)
(29087..30067)
IS5/IS1182 family transposase (29087..30067)
(30222..30106)
ABC transporter (30222..30106)
(30765..30391)
hypothetical protein (30765..30391)
(31147..30821)
theronine dehydrogenase (31147..30821)
(31872..31144)
plasmid SOS inhibition protein A (31872..31144)
psiB (32300..31869)
psiB conjugation system SOS inhibitor PsiB (32300..31869)
(34402..32345)
hypothetical protein (34402..32345)
(34720..34472)
DUF905 domain-containing protein (34720..34472)
(35311..34769)
single-stranded DNA-binding protein (35311..34769)
(35415..35631)
hypothetical protein (35415..35631)
(35926..36245)
hypothetical protein (35926..36245)
(36703..36140)
SAM-dependent methyltransferase (36703..36140)
(38106..36751)
DUF3560 domain-containing protein (38106..36751)
(38388..38158)
hypothetical protein (38388..38158)
(38707..38480)
hypothetical protein (38707..38480)
(38799..39018)
hypothetical protein (38799..39018)
(38933..39193)
hypothetical protein (38933..39193)
(39707..39387)
hypothetical protein (39707..39387)
(39996..39742)
DNA polymerase III subunit theta (39996..39742)
(40658..40233)
antirestriction protein (40658..40233)
(40696..40877)
hypothetical protein (40696..40877)
(41409..41179)
hypothetical protein (41409..41179)
ltrA (43127..41643)
ltrA group II intron reverse transcriptase/maturase (43127..41643)
(43378..43127)
hypothetical protein (43378..43127)
(43533..43958)
peptidase (43533..43958)
(43958..45229)
translesion error-prone DNA polymerase V subunit UmuC (43958..45229)
(45308..45523)
plasmid stabilization protein (45308..45523)
(46744..45546)
transposase (46744..45546)
(46958..47192)
hypothetical protein (46958..47192)
(48009..47219)
hypothetical protein (48009..47219)
(48980..48009)
plasmid-partitioning protein (48980..48009)
(50146..48980)
plasmid-partitioning protein SopA (50146..48980)
(50898..51908)
RepB family plasmid replication initiator protein (50898..51908)
(52442..52245)
hypothetical protein (52442..52245)
(53365..52625)
recombinase (53365..52625)
(54509..55456)
sensor domain-containing diguanylate cyclase (54509..55456)
(55794..55483)
EAL domain-containing protein (55794..55483)
(55859..56782)
IS5/IS1182 family transposase (55859..56782)
(57712..57455)
hypothetical protein (57712..57455)
(58314..59768)
diguanylate cyclase (58314..59768)
(62028..60751)
DUF2254 domain-containing protein (62028..60751)
(64094..62091)
high-affinity choline transporter BetT (64094..62091)
(64937..64240)
IS1 family transposase (64937..64240)
(65009..65101)
PapC protein (65009..65101)
(66335..65128)
IS3 family transposase (66335..66014)
(66426..66910)
IS1 family transposase (66426..66910)
(66926..67468)
ISL3 family transposase (66926..67468)
(68195..67764)
silver-binding protein SilE (68195..67764)
(69921..68446)
two-component sensor histidine kinase (69921..68446)
(70594..69914)
DNA-binding response regulator (70594..69914)
(70784..72169)
hypothetical protein (70784..72169)
(72198..72551)
copper ABC transporter substrate-binding protein (72198..72551)
(72665..73957)
efflux RND transporter periplasmic adaptor subunit (72665..73957)
(73968..77114)
CusA/CzcA family heavy metal efflux RND transporter (73968..77114)
(77201..77641)
hypothetical protein (77201..77641)
(77768..80215)
copper-translocating P-type ATPase (77768..80215)
(80256..80453)
DUF2933 domain-containing protein (80256..80453)
(81224..80487)
peptidase M23 (81224..80487)
(81962..81513)
copper resistance protein (81962..81513)
(82196..84013)
copper resistance protein A (82196..84013)
(84013..84909)
copper resistance protein B (84013..84909)
(84949..85329)
copper resistance protein CopC (84949..85329)
(85334..86263)
copper resistance protein D (85334..86263)
(86318..86998)
DNA-binding response regulator (86318..86998)
(86995..88395)
sensor histidine kinase (86995..88395)
(88612..89046)
copper-binding protein (88612..89046)
(89457..89278)
type II toxin-antitoxin system RelE/ParE family toxin (89457..89278)
(91138..89518)
ISL3 family transposase (91138..89518)
(91200..91709)
porin (91200..91709)
(92256..91759)
N-acetyltransferase (92256..91759)
(92588..92914)
transcriptional regulator (92588..92914)
arsH (92914..93624)
arsH arsenical resistance protein ArsH (92914..93624)
(93633..94178)
RNA polymerase subunit sigma-70 (93633..94178)
(94254..94616)
arsenical resistance operon transcriptional repressor ArsD (94254..94616)
arsA (94635..96391)
arsA arsenical pump-driving ATPase (94635..96391)
(96513..97049)
N-acetyltransferase (96513..97049)
arsC (97507..97082)
arsC arsenate reductase (97507..97082)
(98809..97520)
arsenical efflux pump membrane protein ArsB (98809..97520)
arsA (100608..98857)
arsA arsenical pump-driving ATPase (100608..98857)
(100988..100626)
arsenical resistance operon transcriptional repressor ArsD (100988..100626)
(101388..101038)
transcriptional regulator (101388..101038)
(101746..102015)
hypothetical protein (101746..102015)
(102003..102578)
hypothetical protein (102003..102578)
(102609..103103)
DNA-binding protein (102609..103103)
(103147..103515)
hypothetical protein (103147..103515)
(103549..103752)
hemolysin expression modulator Hha (103549..103752)
(103801..104058)
hypothetical protein (103801..104058)
(104134..104388)
hypothetical protein (104134..104388)
(104564..104830)
DUF1778 domain-containing protein (104564..104830)
(104818..105300)
N-acetyltransferase (104818..105300)
(105512..106858)
ISNCY family transposase (105512..106858)
(108613..107359)
IS3 family transposase (108613..107359)
(109663..108701)
Zn-dependent protease (109663..108701)
(110399..109650)
diguanylate cyclase (110399..109650)
(110587..110375)
diguanylate cyclase (110587..110375)
(110834..110637)
hypothetical protein (110834..110637)
(113629..110834)
ATP-dependent Clp protease ATP-binding subunit (113629..110834)
(114313..113744)
Hsp20/alpha crystallin family protein (114313..113744)
(114629..114348)
DNA-binding protein (114629..114348)
(114825..115264)
IS66 family insertion sequence hypothetical protein (114825..115264)
(115359..115475)
hypothetical protein (115359..115475)
(115660..116357)
IS1 family transposase (115660..116357)
(116616..117596)
IS5/IS1182 family transposase (116616..117596)
(117721..117635)
ABC transporter (117721..117635)
(117773..118099)
hypothetical protein (117773..118099)
(118697..118178)
IS5/IS1182 family transposase (118697..118178)
(119674..118805)
LysR family transcriptional regulator (119674..118805)
(120678..119668)
phosphonate dehydrogenase (120678..119668)
phnE (121514..120687)
phnE phosphonate ABC transporter, permease protein PhnE (121514..120687)
(122386..121523)
phosphate/phosphite/phosphonate ABC transporter substrate-binding protein (122386..121523)
phnC (123210..122383)
phnC phosphonate ABC transporter ATP-binding protein (123210..122383)
(123552..123860)
IS5/IS1182 family transposase (123552..123860)
(124770..124066)
IS6 family transposase IS15DIV (124770..124066)
(124834..125172)
hypothetical protein (124834..125172)
(125177..125383)
hypothetical protein (125177..125383)
(125666..125394)
IS1 family transposase (125666..125394)
(125765..127198)
DNA cytosine methyltransferase (125765..127198)
(128440..127232)
restriction endonuclease (128440..127232)
(128665..128453)
resolvase (128665..128453)
(128652..128735)
glutathione S-transferase (128652..128735)
(129471..128707)
IS6 family transposase (129471..128707)
(129500..129655)
NTP-binding protein (129500..129655)
(129880..129614)
plasmid mobilization relaxosome protein MobC (129880..129614)
(130583..130101)
trimethoprim-resistant dihydrofolate reductase DfrA14 (130583..130101)
(130730..131743)
integron integrase (130730..131743)
(131682..131996)
transposase (131682..131996)
(132136..132270)
hypothetical protein (132136..132270)
(132333..133037)
IS6 family transposase IS15DIV (132333..133037)
(133091..133567)
IS6 family transposase (133091..133567)
(134035..133619)
S-formylglutathione hydrolase (134035..133619)
(135166..134057)
S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase (135166..134057)
(136445..135261)
tetracycline efflux MFS transporter Tet(D) (136445..135261)
(136541..137197)
TetR family transcriptional regulator (136541..137197)
(137209..137913)
IS6 family transposase IS15DIV (137209..137913)
(137966..138121)
IS30 family transposase (137966..138121)
(138222..139034)
subclass B1 metallo-beta-lactamase NDM-1 (138222..139034)
(139038..139403)
bleomycin binding protein Ble-MBL (139038..139403)
(139408..140067)
phosphoribosylanthranilate isomerase (139408..140067)
(140783..139989)
class C beta-lactamase (140783..139989)
(140894..141769)
LysR family transcriptional regulator (140894..141769)
hypA (142138..141773)
hypA hydrogenase maturation nickel metallochaperone HypA (142138..141773)
(142031..142366)
QacE family quaternary ammonium compound efflux SMR transporter (142031..142366)
(142360..143199)
sulfonamide-resistant dihydropteroate synthase Sul1 (142360..143199)
(143604..145145)
IS91 family transposase (143604..145145)
(145379..146218)
IS5 family transposase (145379..146218)
(146322..146516)
hypothetical protein (146322..146516)
(146544..147317)
ArmA family 16S rRNA (guanine(1405)-N(7))-methyltransferase (146544..147317)
(147579..147298)
hypothetical protein (147579..147298)
(147984..147799)
hypothetical protein (147984..147799)
(148033..149217)
IS4 family transposase ISEc29 (148033..149217)
(149616..151091)
ABC-F type ribosomal protection protein Msr(E) (149616..151091)
(151147..152031)
Mph(E) family macrolide 2'-phosphotransferase (151147..152031)
(152932..152390)
DNA-binding protein (152932..152390)
(153826..152999)
RepB family plasmid replication initiator protein (153826..152999)
(153817..154521)
IS6 family transposase IS15DIV (153817..154521)
(155046..154555)
hypothetical protein (155046..154555)
(155153..155890)
resolvase (155153..155890)
(155887..156111)
hypothetical protein (155887..156111)
(156322..156861)
IS91 family transposase (156322..156861)
(157669..156833)
aminoglycoside O-phosphotransferase APH(6)-Id (157669..156833)
(158472..157669)
aminoglycoside O-phosphotransferase APH(3'')-Ib (158472..157669)
folP (159348..158533)
folP sulfonamide-resistant dihydropteroate synthase Sul2 (159348..158533)
(159372..159449)
transcriptional regulator (159372..159449)
(159678..159854)
integrase (159678..159854)
(161040..160036)
IS110 family transposase (161040..160036)
(162454..161444)
zinc-binding alcohol dehydrogenase family protein (162454..161444)
(162692..162477)
hypothetical protein (162692..162477)
lacI (162915..163997)
lacI lac repressor (162915..163997)
lacZ (164119..167193)
lacZ beta-galactosidase (164119..167193)
lacY (167245..168498)
lacY MFS transporter (167245..168498)
(168590..169559)
IS5/IS1182 family transposase (168590..169559)
(170204..172513)
ATPase (170204..172513)
(172517..173833)
ATP-binding protein (172517..173833)
(173830..176025)
DEAD/DEAH box helicase (173830..176025)
(176647..176835)
hypothetical protein (176647..176835)
(176979..177167)
hypothetical protein (176979..177167)
repA (178330..177473)
repA incFII family plasmid replication initiator RepA (178330..177473)
tap (178400..178323)
tap RepA leader peptide Tap (178400..178323)
(178895..178617)
replication protein (178895..178617)
(179766..179215)
phospholipase D family protein (179766..179215)
(180253..180052)
bacteriocin immunity protein (180253..180052)
(181904..180366)
IS66 family transposase (181904..180366)
(182300..181953)
IS66 family insertion sequence hypothetical protein (182300..181953)
(182701..182297)
IS66 family insertion sequence hypothetical protein (182701..182297)
(182700..182783)
cytochrome B562 (182700..182783)
(182779..182934)
IS3 family transposase (182779..182934)
(188890..183155)
DNA helicase UvrD (188890..183155)
(191119..189077)
DUF262 domain-containing protein (191119..189077)
(192563..191112)
DUF262 domain-containing protein (192563..191112)
(192896..192588)
IS3 family transposase (192896..192588)
(193152..192913)
IS110 family transposase (193152..192913)
(193336..193151)
IS1 family transposase (193336..193151)
(193391..193293)
glycosyl transferase (193391..193293)
(194178..193423)
M48 family peptidase (194178..193423)
(197459..194175)
type I restriction endonuclease subunit R (197459..194175)
(198195..197512)
YecA family protein (198195..197512)
(199466..198192)
restriction endonuclease subunit S (199466..198192)
(200979..199456)
type I restriction-modification system subunit M (200979..199456)
(201980..201283)
IS1 family transposase (201980..201283)
(202708..202112)
hypothetical protein (202708..202112)
(203468..202875)
conjugal transfer protein (203468..202875)
traX (204350..203625)
traX type-F conjugative transfer system pilin acetylase TraX (204350..203625)
traI (209655..204394)
traI conjugative transfer relaxase/helicase TraI (209655..204394)
traD (211967..209655)
traD type IV conjugative transfer system coupling protein TraD (211967..209655)
(212477..212094)
hypothetical protein (212477..212094)
(213707..212976)
complement resistance protein TraT (213707..212976)
(214426..213893)
conjugal transfer protein TraS (214426..213893)
(217278..214429)
conjugal transfer protein TraG (217278..214429)
(218645..217278)
conjugal transfer protein TraH (218645..217278)
(219078..218635)
conjugal transfer protein TrbF (219078..218635)
trbB (219681..219124)
trbB type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB (219681..219124)
(219892..219653)
conjugal transfer protein TraQ (219892..219653)
traF (220655..219903)
traF type-F conjugative transfer system pilin assembly protein TraF (220655..219903)
(221002..220676)
hypothetical protein (221002..220676)
(221263..221015)
hypothetical protein (221263..221015)
(221495..221241)
conjugal transfer protein TrbE (221495..221241)