INTEGRALL

The Integron Database

Klebsiella pneumoniae
Accession Number: CP026179
Source: USA
Journal: Unpublished
Published: 29-JAN-2018
Title: Genomic Analysis of Hospital Plumbing Reveals Diverse Reservoir of Bacterial Plasmids Conferring Carbapenem Resistance
Authors: Weingarten,R.A., Johnson,R.C., Conlan,S., Ramsburg,A.M., Dekker,J.P., Lau,A.F., Khil,P., Odom,R.T., Deming,C., Park,M., Thomas,P.J., Henderson,D.K., Palmore,T.N., Segre,J.A., Frank,K.M.
Remarks: Class 1 integron. In191
Promoter: PcH1
Gene Product Sequence
(2473..1)
DUF4158 domain-containing protein (2473..1)
(2632..2922)
nucleotidyltransferase (2632..2922)
(2919..3320)
DUF86 domain-containing protein (2919..3320)
(3310..3666)
cupin domain-containing protein (3310..3666)
(3921..4247)
hypothetical protein (3921..4247)
(4244..4744)
transposase (4244..4744)
(4741..5112)
hypothetical protein (4741..5112)
(5106..5663)
recombinase family protein (5106..5663)
(5742..6746)
IS110-like element IS5075 family transposase (5742..6746)
(7023..7352)
arsenical resistance protein ArsH (7023..7352)
arsC (7838..7410)
arsC arsenate reductase (glutaredoxin) (7838..7410)
(9171..7888)
arsenical efflux pump membrane protein ArsB (9171..7888)
(9620..9267)
transcriptional regulator (9620..9267)
(10104..11582)
SulP family inorganic anion transporter (10104..11582)
(11601..12428)
universal stress protein (11601..12428)
(13696..12500)
MFS transporter (13696..12500)
(14225..14599)
fluoride efflux transporter CrcB (14225..14599)
nhaA (14874..16022)
nhaA Na+/H+ antiporter NhaA (14874..16022)
(16609..16376)
QacE family quaternary ammonium compound efflux SMR transporter (16609..16376)
(16675..17379)
IS6 family transposase IS15DIV (16675..17379)
(17438..17325)
5,10-methylenetetrahydrofolate reductase (17438..17325)
(17611..18168)
recombinase (17611..18168)
(18402..18956)
aminoglycoside N-acetyltransferase AAC(6')-Ib' (18402..18956)
aadA1 (19026..19814)
aadA1 ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA1 (19026..19814)
(19874..20698)
oxacillin-hydrolyzing class D beta-lactamase OXA-9 (19874..20698)
(20898..21215)
hypothetical protein (20898..21215)
blaTEM (21398..22258)
blaTEM class A broad-spectrum beta-lactamase TEM-1 (21398..22258)
(22468..22872)
IS91 family transposase (22468..22872)
(23710..23162)
IS110 family transposase (23710..23162)
merR (24186..23731)
merR Hg(II)-responsive transcriptional regulator (24186..23731)
(24258..24608)
mercuric transporter (24258..24608)
merP (24624..24899)
merP mercuric transporter periplasmic component (24624..24899)
(24927..25334)
mercury transport protein MerC (24927..25334)
(25373..27055)
mercury(II) reductase (25373..27055)
merD (27073..27438)
merD transcriptional regulator (27073..27438)
(27435..27671)
mercury resistance protein (27435..27671)
(27774..27655)
mercury resistance protein (27774..27655)
(27737..27949)
DUF3330 domain-containing protein (27737..27949)
(27976..28041)
transposase (27976..28041)
(28079..28636)
recombinase family protein (28079..28636)
(28639..31611)
Tn3 family transposase (28639..31611)
(32136..31651)
IS110 family transposase (32136..31651)
(32375..32160)
hypothetical protein (32375..32160)
aph(6)-I (33130..32294)
aph(6)-I aminoglycoside O-phosphotransferase APH(6)-Id (33130..32294)
(33933..33130)
aminoglycoside O-phosphotransferase APH(3'')-Ib (33933..33130)
(34809..33994)
sulfonamide-resistant dihydropteroate synthase Sul2 (34809..33994)
(34833..34910)
transcriptional regulator (34833..34910)
(35139..35315)
DUF4102 domain-containing protein (35139..35315)
(36501..35497)
IS110-like element IS5075 family transposase (36501..35497)
(37980..36580)
Tn3 family transposase (37980..36580)
(38045..38749)
IS6 family transposase IS15DIV (38045..38749)
(38808..38695)
AraC family transcriptional regulator (38808..38695)
(38801..39172)
Tn3 family transposase (38801..39172)
(39930..39226)
IS6 family transposase IS15DIV (39930..39226)
(39996..40493)
Tn3 family transposase (39996..40493)
(40868..40503)
FipA (40868..40503)
(44104..40868)
conjugative relaxase (44104..40868)
(45633..44104)
DUF87 domain-containing protein (45633..44104)
(46051..45635)
traK protein (46051..45635)
(46824..46961)
StbA (46824..46961)
(46970..47686)
StdB protein (46970..47686)
(47688..48056)
StbC (47688..48056)
(48349..48582)
hypothetical protein (48349..48582)
(49013..48693)
CcgAII protein (49013..48693)
(49247..49068)
cobalamin biosynthesis protein CbiX (49247..49068)
(50483..49974)
antirestriction protein (50483..49974)
(52168..51836)
hypothetical protein (52168..51836)
(52661..52377)
cobalamin biosynthesis protein CbiX (52661..52377)
(53089..52730)
hypothetical protein (53089..52730)
(53382..53086)
cobalamin biosynthesis protein CbiX (53382..53086)
(54507..54268)
cobalamin biosynthesis protein CbiX (54507..54268)
(54921..54517)
antirestriction protein ArdR (54921..54517)
(55404..54979)
hypothetical protein (55404..54979)
(55692..55496)
hypothetical protein (55692..55496)
(55819..56259)
peptidase (55819..56259)
(56247..57512)
translesion error-prone DNA polymerase V subunit UmuC (56247..57512)
(57663..58454)
sprT domain-containing protein (57663..58454)
(58810..58469)
ArdK family transcriptional regulator (58810..58469)
(59370..60089)
RepB family plasmid replication initiator protein (59370..60089)
(60696..61694)
hypothetical protein (60696..61694)
(62615..62046)
recombinase family protein (62615..62046)
(63069..62755)
transposase (63069..62755)
(64021..63008)
integron integrase (64021..63008)
dfrA (64168..64650)
dfrA trimethoprim-resistant dihydrofolate reductase DfrA14 (64168..64650)
(64871..65137)
plasmid mobilization relaxosome protein MobC (64871..65137)
(65251..65096)
NTP-binding protein (65251..65096)
(65280..66044)
IS6 family transposase IS6100 (65280..66044)
(66102..66016)
glutathione S-transferase (66102..66016)
(66086..66298)
resolvase (66086..66298)
(66311..67519)
restriction endonuclease (66311..67519)
(68968..67553)
DNA (cytosine-5-)-methyltransferase (68968..67553)
(71901..69004)
Tn3-like element Tn5403 family transposase (71901..69004)
(71996..72601)
DNA resolvase (71996..72601)
(72915..74234)
IS1182 family transposase ISKpn6 (72915..74234)
(75365..74484)
carbapenem-hydrolyzing class A beta-lactamase KPC-2 (75365..74484)
(75755..75525)
hypothetical protein (75755..75525)
(75838..75752)
AAA family ATPase (75838..75752)
(76594..75890)
IS6 family transposase IS15DIV (76594..75890)
(76716..77021)
chemotaxis protein (76716..77021)
pspF (77023..77178)
pspF phage shock protein operon transcriptional activator (77023..77178)
(77272..77916)
quinolone resistance pentapeptide repeat protein QnrB19 (77272..77916)
(78242..77925)
hypothetical protein (78242..77925)
(79668..78406)
IS1380 family transposase ISEc9 (79668..78406)
(79855..81126)
chemotaxis protein (79855..81126)
(81454..82215)
DeoR/GlpR transcriptional regulator (81454..82215)
(83096..82236)
class A extended-spectrum beta-lactamase SHV-12 (83096..82236)
(83242..83060)
hypothetical protein (83242..83060)
(83233..83937)
IS6 family transposase IS15DIV (83233..83937)
(84094..83990)
QacE family quaternary ammonium compound efflux SMR transporter (84094..83990)
(84783..84226)
recombinase family protein (84783..84226)
(84945..87941)
Tn3 family transposase (84945..87941)
(88476..87988)
LacI family transcriptional regulator (88476..87988)
(89239..89039)
glycogen synthesis protein GlgS (89239..89039)
(90508..89540)
IS5-like element IS903B family transposase (90508..89540)
(90881..93073)
1,4-alpha-glucan branching enzyme (90881..93073)
glgC (93203..94486)
glgC glucose-1-phosphate adenylyltransferase (93203..94486)
(94575..96008)
glycogen synthase GlgA (94575..96008)
(96027..98474)
glycogen phosphorylase (96027..98474)
(98588..100231)
alpha-D-glucose phosphate-specific phosphoglucomutase (98588..100231)
(100356..100922)
LuxR family transcriptional regulator (100356..100922)
(101257..101535)
hypothetical protein (101257..101535)
(101754..101563)
hypothetical protein (101754..101563)
(103172..101775)
helix-turn-helix domain-containing protein (103172..101775)
(103756..103361)
helix-turn-helix domain-containing protein (103756..103361)
(105151..103805)
transposase (105151..103805)
(105377..106009)
hypothetical protein (105377..106009)
(107441..106038)
ISNCY family transposase ISKpn21 (107441..106038)
(107553..109085)
IS3-like element ISKpn38 family transposase (107553..109085)
(109726..109244)
N-acetyltransferase (109726..109244)
(109980..109714)
DUF1778 domain-containing protein (109980..109714)
(110187..110381)
hypothetical protein (110187..110381)
(110655..110425)
hypothetical protein (110655..110425)
(110872..110669)
hemolysin expression modulator Hha (110872..110669)
(111424..110933)
DNA-binding protein (111424..110933)
(112769..111558)
hypothetical protein (112769..111558)
(113014..112766)
hypothetical protein (113014..112766)
(113372..113722)
transcriptional regulator (113372..113722)
(113774..114136)
arsenical resistance operon transcriptional repressor ArsD (113774..114136)
arsA (114154..115905)
arsA arsenical pump-driving ATPase (114154..115905)
(115953..117242)
arsenical efflux pump membrane protein ArsB (115953..117242)
arsC (117255..117680)
arsC arsenate reductase (glutaredoxin) (117255..117680)
(118141..117713)
N-acetyltransferase (118141..117713)
(119261..118263)
hypothetical protein (119261..118263)
(119563..119255)
IS3 family transposase (119563..119255)
(120656..119580)
IS110 family transposase (120656..119580)
(120790..120578)
transposase (120790..120578)
(121117..120938)
IS3 family transposase (121117..120938)
ltrA (122721..121198)
ltrA group II intron reverse transcriptase/maturase (122721..121198)
(123015..123452)
hypothetical protein (123015..123452)
(124050..123379)
IS3 family transposase (124050..123379)
(124236..124367)
ISNCY family transposase (124236..124367)
(124975..124364)
DUF2913 domain-containing protein (124975..124364)
(125310..125029)
cytoplasmic protein (125310..125029)
(125483..125818)
C2H2-type zinc finger protein (125483..125818)
(126369..126557)
hypothetical protein (126369..126557)
repA (127724..126861)
repA incFII family plasmid replication initiator RepA (127724..126861)
tap (127794..127717)
tap RepA leader peptide Tap (127794..127717)
(127873..127965)
replication protein RepA (127873..127965)
(128283..128017)
ribbon-helix-helix protein, CopG family (128283..128017)
(129021..128473)
phospholipase D family protein (129021..128473)
(129796..129206)
hypothetical protein (129796..129206)
(132252..130510)
conjugal transfer protein TraI (132252..130510)
(133521..132814)
conjugal transfer protein TraI (133521..132814)
(135024..134164)
conjugal transfer protein TraI (135024..134164)
traD (137158..135026)
traD type IV conjugative transfer system coupling protein TraD (137158..135026)
(137852..137289)
hypothetical protein (137852..137289)
(140731..137861)
conjugal transfer protein TraG (140731..137861)
(142098..140734)
conjugal transfer protein TraH (142098..140734)
trbB (142649..142095)
trbB type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB (142649..142095)
traF (143463..142693)
traF type-F conjugative transfer system pilin assembly protein TraF (143463..142693)
traN (145400..143463)
traN type-F conjugative transfer system mating-pair stabilization protein TraN (145400..143463)
trbC (145817..145428)
trbC type-F conjugative transfer system pilin assembly protein TrbC (145817..145428)
(146824..145826)
conjugal transfer protein TraU (146824..145826)
traW (147582..146821)
traW type-F conjugative transfer system protein TraW (147582..146821)
(147844..147467)
hypothetical protein (147844..147467)
traC (150510..147862)
traC type IV secretion system protein TraC (150510..147862)
traV (151022..150492)
traV type IV conjugative transfer system protein TraV (151022..150492)
(151424..151035)
hypothetical protein (151424..151035)
(152774..151443)
hypothetical protein (152774..151443)
(153529..152771)
hypothetical protein (153529..152771)
(154067..153480)
hypothetical protein (154067..153480)
traL (154423..154127)
traL type IV conjugative transfer system protein TraL (154423..154127)
(154743..154438)
TraA fimbrial protein precursor (154743..154438)
(155073..154768)
TraA fimbrial protein precursor (155073..154768)
(155417..155214)
TraY domain-containing protein (155417..155214)
(155731..156576)
BetR domain protein (155731..156576)
(156573..157568)
hypothetical protein (156573..157568)
(157555..158058)
oxidoreductase (157555..158058)
(158055..159773)
hybrid sensor histidine kinase/response regulator (158055..159773)
(160062..159802)
hypothetical protein (160062..159802)
(160646..161086)
lytic transglycosylase (160646..161086)
(161129..161446)
hypothetical protein (161129..161446)
(161815..161507)
hypothetical protein (161815..161507)
(162696..161875)
DUF945 domain-containing protein (162696..161875)
(162799..163017)
hypothetical protein (162799..163017)
(164355..163522)
N-6 DNA methylase (164355..163522)
(164550..164404)
succinate dehydrogenase flavoprotein subunit (164550..164404)
(164992..164645)
hypothetical protein (164992..164645)
(165439..165059)
hypothetical protein (165439..165059)
(165947..166138)
hypothetical protein (165947..166138)
(166050..166262)
hypothetical protein (166050..166262)
(166577..166161)
transcriptional regulator (166577..166161)
(166885..166574)
cytoplasmic protein (166885..166574)
(167216..166992)
hypothetical protein (167216..166992)
(167433..167227)
hypothetical protein (167433..167227)
(167554..167459)
single-stranded DNA-binding protein (167554..167459)
(167538..167757)
hypothetical protein (167538..167757)
(168420..168070)
hypothetical protein (168420..168070)
(168689..168417)
hypothetical protein (168689..168417)
(169769..169047)
plasmid SOS inhibition protein A (169769..169047)
psiB (170197..169766)
psiB conjugation system SOS inhibitor PsiB (170197..169766)
(172252..170243)
hypothetical protein (172252..170243)
(172563..172321)
DUF905 domain-containing protein (172563..172321)
(173123..172611)
single-stranded DNA-binding protein (173123..172611)
(173227..173446)
hypothetical protein (173227..173446)
(173361..173621)
hypothetical protein (173361..173621)
(174265..174053)
hypothetical protein (174265..174053)
(175016..174453)
SAM-dependent methyltransferase (175016..174453)
(176419..175064)
hydrolase (176419..175064)
(176651..176523)
single-stranded DNA-binding protein (176651..176523)
(176983..176784)
hypothetical protein (176983..176784)
(177610..177386)
hypothetical protein (177610..177386)
(177719..177922)
hypothetical protein (177719..177922)
(178440..178763)
LuxR family transcriptional regulator (178440..178763)
(179420..178992)
antirestriction protein (179420..178992)
(180687..179923)
hypothetical protein (180687..179923)
(181163..180744)
DUF1380 domain-containing protein (181163..180744)
(181394..181173)
hypothetical protein (181394..181173)
(182095..181394)
DNA methylase (182095..181394)
(182370..182167)
hypothetical protein (182370..182167)
(182646..182803)
adenine methylase (182646..182803)
(183007..183261)
hypothetical protein (183007..183261)
(185303..183264)
ATP-dependent helicase (185303..183264)
(186286..185300)
hypothetical protein (186286..185300)
(187562..187170)
plasmid stability protein (187562..187170)
(188540..187566)
StbA family protein (188540..187566)
(189154..188780)
hypothetical protein (189154..188780)
(189786..189154)
hypothetical protein (189786..189154)
(190448..190212)
hypothetical protein (190448..190212)
(191534..190779)
replication initiation protein RepE (191534..190779)
(192076..192438)
hypothetical protein (192076..192438)
(193241..192456)
phage integrase family protein (193241..192456)
(193684..193292)
hypothetical protein (193684..193292)
(194737..193793)
hypothetical protein (194737..193793)
(195271..194898)
hypothetical protein (195271..194898)
(195324..195554)
AbrB/MazE/SpoVT family DNA-binding domain-containing protein (195324..195554)
(195551..195967)
PIN domain-containing protein (195551..195967)
(196886..196008)
DUF3644 domain-containing protein (196886..196008)
(197548..198825)
colicin V secretion protein CvaA (197548..198825)
(198815..200923)
peptidase domain-containing ABC transporter (198815..200923)
(200923..201558)
CPBP family intramembrane metalloprotease (200923..201558)
(202007..201666)
hypothetical protein (202007..201666)
(202330..203266)
CAAX protease (202330..203266)
(203897..203457)
hypothetical protein (203897..203457)
(204509..203916)
hypothetical protein (204509..203916)
(204817..204608)
hypothetical protein (204817..204608)
(204801..205031)
AbrB/MazE/SpoVT family DNA-binding domain-containing protein (204801..205031)
(205028..205444)
PIN domain nuclease (205028..205444)
(205518..207077)
ATP-dependent endonuclease (205518..207077)
(208087..207119)
IS5/IS1182 family transposase (208087..207119)
(208131..209153)
DNA helicase UvrD (208131..209153)
(209697..210605)
HNH endonuclease (209697..210605)
(211141..210791)
DUF305 domain-containing protein (211141..210791)
silE (211720..211289)
silE silver-binding protein SilE (211720..211289)
(213446..211971)
HAMP domain-containing protein (213446..211971)
(214119..213439)
DNA-binding response regulator (214119..213439)
(214309..215694)
hypothetical protein (214309..215694)
(215723..216076)
copper ABC transporter substrate-binding protein (215723..216076)
(216190..217482)
efflux RND transporter periplasmic adaptor subunit (216190..217482)
(217493..220639)
CusA/CzcA family heavy metal efflux RND transporter (217493..220639)
(220726..221166)
hypothetical protein (220726..221166)
(221293..223740)
copper-translocating P-type ATPase (221293..223740)
(223781..223978)
DUF2933 domain-containing protein (223781..223978)
(224749..224012)
peptidase M23 (224749..224012)
(225487..225038)
copper resistance protein (225487..225038)
pcoA (225721..227538)
pcoA multicopper oxidase PcoA (225721..227538)
(227538..228434)
copper resistance protein B (227538..228434)
pcoC (228474..228854)
pcoC copper resistance system chaperone PcoC (228474..228854)
(228859..229788)
copper resistance protein D (228859..229788)
(229843..230523)
DNA-binding response regulator (229843..230523)
(230520..231920)
sensor histidine kinase (230520..231920)
(232136..232570)
copper-binding protein (232136..232570)
(232912..232750)
type II toxin-antitoxin system RelE/ParE family toxin (232912..232750)
(233068..232949)
type II toxin-antitoxin system RelE/ParE family toxin (233068..232949)
(233213..233034)
antitoxin (233213..233034)
(233527..233790)
hypothetical protein (233527..233790)
(233787..234353)
hypothetical protein (233787..234353)
(234384..234878)
DNA-binding protein (234384..234878)
(234939..235142)
transcriptional regulator (234939..235142)
(235191..235448)
hypothetical protein (235191..235448)
(235524..235778)
hypothetical protein (235524..235778)
(237081..236077)
IS110-like element IS5075 family transposase (237081..236077)