INTEGRALL

The Integron Database

Klebsiella pneumoniae
Accession Number: CP031850
Source: blood - China: Hangzhou
Journal: Clin. Microbiol. Infect. (2019) In press
Published: 19-APR-2019
Title: Emergence of a ST2570 Klebsiella pneumoniae isolate carrying mcr-1 and blaCTX-M-14 recovered from a bloodstream infection in China
Authors: Ruan,Z., Sun,Q., Jia,H., Huang,C., Zhou,W., Xie,X., Zhang,J.
Remarks: Class 1 integron. In641
Promoter: PcH1
Gene Product Sequence
(1..876)
RepB family plasmid replication initiator protein (1..876)
(1254..1502)
hypothetical protein (1254..1502)
(2025..2378)
pili assembly chaperone (2025..2378)
(2429..2746)
plasmid transfer protein (2429..2746)
(2758..3546)
pilus assembly protein (2758..3546)
(3546..4817)
TrhK (3546..4817)
(4819..5280)
hypothetical protein (4819..5280)
(5270..6625)
conjugal transfer protein TraB (5270..6625)
(6633..7115)
transcriptional regulator (6633..7115)
(7153..7986)
DsbC family protein (7153..7986)
(7996..8946)
TrhV (7996..8946)
(8955..11636)
conjugal transfer protein (8955..11636)
(15473..16726)
ParA family protein (15473..16726)
(16723..17727)
peptide transporter (16723..17727)
(18178..17789)
hypothetical protein (18178..17789)
(18696..18175)
hypothetical protein (18696..18175)
(19525..18689)
hypothetical protein (19525..18689)
(20469..19522)
hypothetical protein (20469..19522)
(20833..21870)
stbA family protein (20833..21870)
(21882..22520)
hypothetical protein (21882..22520)
(22924..23376)
transfer repressor (22924..23376)
(23366..23791)
htdF (23366..23791)
(23800..24354)
plasmid transfer protein (23800..24354)
(24474..28778)
hypothetical protein (24474..28778)
lepB (29056..29568)
lepB signal peptidase I (29056..29568)
(29555..31066)
conjugal transfer protein (29555..31066)
(31256..32266)
plasmid transfer protein (31256..32266)
(32285..35473)
conjugal transfer protein TraN (32285..35473)
(36374..35502)
hypothetical protein (36374..35502)
(36554..38338)
ATP-dependent helicase (36554..38338)
(38733..39605)
hypothetical protein (38733..39605)
(39663..40040)
hypothetical protein (39663..40040)
(40101..41078)
hypothetical protein (40101..41078)
(41136..42194)
ATP-binding protein (41136..42194)
(42563..43690)
DUF3150 domain-containing protein (42563..43690)
(43768..45780)
VWA domain-containing protein (43768..45780)
(45852..46073)
hypothetical protein (45852..46073)
(46187..47419)
hypothetical protein (46187..47419)
(47690..48211)
hypothetical protein (47690..48211)
(48290..49168)
hypothetical protein (48290..49168)
(49239..50174)
hypothetical protein (49239..50174)
(50243..51163)
hypothetical protein (50243..51163)
(51230..52168)
hypothetical protein (51230..52168)
(52340..53296)
hypothetical protein (52340..53296)
(53560..53835)
hypothetical protein (53560..53835)
(53880..54470)
hypothetical protein (53880..54470)
(54478..54735)
hypothetical protein (54478..54735)
(54809..55345)
hypothetical protein (54809..55345)
(55362..55808)
hypothetical protein (55362..55808)
(55881..56861)
DNA replication protein (55881..56861)
(56871..57746)
hypothetical protein (56871..57746)
(57776..58750)
IS30-like element ISApl1 family transposase (57776..58750)
(58946..60571)
phosphoethanolamine--lipid A transferase MCR-1.1 (58946..60571)
(60619..61365)
PAP2 family protein (60619..61365)
(61391..61735)
hypothetical protein (61391..61735)
(62932..61757)
recombinase (62932..61757)
(63103..63315)
hypothetical protein (63103..63315)
(63676..64758)
hypothetical protein (63676..64758)
(66424..64925)
kinase (66424..64925)
(68087..66450)
protein phosphatase 2C domain-containing protein (68087..66450)
(69127..68087)
VWA domain-containing protein (69127..68087)
(69851..69213)
VWA domain-containing protein (69851..69213)
(70492..69851)
tellurium resistance protein TerX (70492..69851)
(71153..70515)
VWA domain-containing protein (71153..70515)
(72083..71616)
tellurium resistance protein TerW (72083..71616)
(73309..72101)
DUF4236 domain-containing protein (73309..72101)
(74276..73320)
citrate lyase subunit beta (74276..73320)
(75355..74276)
hypothetical protein (75355..74276)
(76130..75357)
hypothetical protein (76130..75357)
(77265..76123)
adenine/guanine phosphoribosyltransferase (77265..76123)
(78333..77275)
carbamoyl-phosphate synthase large chain (78333..77275)
(78657..79238)
tellurium resistance protein TerZ (78657..79238)
(79238..80395)
tellurium resistance protein TerA (79238..80395)
(80418..80873)
Tellurite resistance protein TerB (80418..80873)
(80896..81936)
tellurium resistance membrane protein TerC (80896..81936)
(81985..82563)
TerD family protein (81985..82563)
(82631..83206)
TerD family protein (82631..83206)
(83237..83441)
hypothetical protein (83237..83441)
(83635..84876)
tellurium resistance protein TerF (83635..84876)
(85720..85439)
hypothetical protein (85720..85439)
(85961..85770)
hypothetical protein (85961..85770)
(86424..86053)
hypothetical protein (86424..86053)
(86767..87159)
hypothetical protein (86767..87159)
(87138..87449)
hypothetical protein (87138..87449)
(87763..88056)
XRE family transcriptional regulator (87763..88056)
(88061..89386)
type II toxin-antitoxin system HipA family toxin (88061..89386)
(89447..89653)
hypothetical protein (89447..89653)
(89755..90165)
hypothetical protein (89755..90165)
(90178..90993)
HNH endonuclease (90178..90993)
(91247..91672)
hypothetical protein (91247..91672)
(92221..92529)
hypothetical protein (92221..92529)
(92545..93402)
HNH endonuclease (92545..93402)
(93464..93712)
hypothetical protein (93464..93712)
(94417..93686)
Tn3 family transposase (94417..93686)
(94676..94251)
DUF4158 domain-containing protein (94676..94251)
(94844..95248)
resolvase (94844..95248)
(96509..95376)
permease (96509..95376)
(96615..96938)
ArsR family transcriptional regulator (96615..96938)
(96985..97083)
glycosyltransferase (96985..97083)
(97040..97416)
IS1 family transposase (97040..97416)
(97481..98185)
IS6 family transposase IS15DIV (97481..98185)
(98244..98131)
adenine-specific DNA-methyltransferase (98244..98131)
mph(A) (98307..99212)
mph(A) Mph(A) family macrolide 2'-phosphotransferase (98307..99212)
(99209..100447)
MFS transporter (99209..100447)
(100447..101031)
TetR/AcrR family transcriptional regulator (100447..101031)
(100977..101333)
hypothetical protein (100977..101333)
(101463..101552)
type VII secretion-associated protein (101463..101552)
(102288..101524)
IS6-like element IS6100 family transposase (102288..101524)
(102317..102436)
NTP-binding protein (102317..102436)
(103160..102456)
IS6 family transposase IS15DIV (103160..102456)
(103503..103225)
DNA (cytosine-5-)-methyltransferase (103503..103225)
(103718..104233)
thermonuclease family protein (103718..104233)
(104236..105132)
hypothetical protein (104236..105132)
(105354..105587)
hypothetical protein (105354..105587)
(105633..105887)
hypothetical protein (105633..105887)
(105925..106212)
hypothetical protein (105925..106212)
(106249..106479)
hypothetical protein (106249..106479)
(106816..107277)
hypothetical protein (106816..107277)
(107307..107714)
hypothetical protein (107307..107714)
(108082..107765)
hypothetical protein (108082..107765)
(108809..108459)
hypothetical protein (108809..108459)
(110433..108919)
Tn3 family transposase (110433..108919)
(110499..111203)
IS6 family transposase IS15DIV (110499..111203)
(111209..111955)
winged helix family transcriptional regulator (111209..111955)
(111955..112473)
hypothetical protein (111955..112473)
(112894..112478)
fosfomycin resistance glutathione transferase FosA3 (112894..112478)
(113471..113154)
IS5/IS1182 family transposase (113471..113154)
(114381..113506)
class A extended-spectrum beta-lactamase CTX-M-14 (114381..113506)
(114625..114738)
5,10-methylenetetrahydrofolate reductase (114625..114738)
(115388..114684)
IS6 family transposase IS15DIV (115388..114684)
(115502..116278)
aminoglycoside N-acetyltransferase AAC(3)-IV (115502..116278)
(116299..116520)
hypothetical protein (116299..116520)
aph(4)-Ia (116507..117532)
aph(4)-Ia aminoglycoside O-phosphotransferase APH(4)-Ia (116507..117532)
(117538..117903)
aminoglycoside N(3)-acetyltransferase (117538..117903)
(118706..117954)
IS6 family transposase (118706..117954)
(118792..120291)
Tn3 family transposase (118792..120291)
(120327..120479)
phenol hydroxylase (120327..120479)
(120517..121002)
phenol hydroxylase (120517..121002)
(121092..120988)
class A beta-lactamase (121092..120988)
(121166..121089)
transcriptional regulator (121166..121089)
(122289..121199)
IS4 family transposase ISAba1 (122289..121749)
sul2 (122379..123194)
sul2 sulfonamide-resistant dihydropteroate synthase Sul2 (122379..123194)
(123281..123583)
phosphoglucosamine mutase (123281..123583)
(123728..123477)
hypothetical protein (123728..123477)
(125252..123759)
IS91 family transposase (125252..123759)
(125669..125364)
LysR family transcriptional regulator (125669..125364)
floR (126911..125697)
floR chloramphenicol/florfenicol efflux MFS transporter FloR (126911..125697)
(128012..127128)
DUF3363 domain-containing protein (128012..127128)
(128879..128043)
IS91 family transposase (128879..128043)
(128937..129641)
IS6 family transposase IS1006 (128937..129641)
(130115..129726)
hypothetical protein (130115..129726)
(131384..130380)
IS110-like element IS4321 family transposase (131384..130380)
(134414..131463)
Tn3-like element TnAs3 family transposase (134414..131463)
(134977..134417)
recombinase family protein (134977..134417)
(135717..135103)
DUF3330 domain-containing protein (135717..135103)
(136669..135656)
class 1 integron integrase IntI1 (136669..135656)
estX (136836..137678)
estX alpha/beta fold putative hydrolase EstX (136836..137678)
(137774..138382)
HAD-IB family hydrolase (137774..138382)
(138440..139231)
ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA2 (138440..139231)
(139493..140752)
chloramphenicol efflux MFS transporter CmlA1 (139493..140752)
aadA1 (140845..141636)
aadA1 ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA1 (140845..141636)
qac (141806..142138)
qac quaternary ammonium compound efflux SMR transporter QacL (141806..142138)
(142278..142463)
hypothetical protein (142278..142463)
(143038..142403)
IS256 family transposase (143038..142403)
sul3 (144109..143318)
sul3 sulfonamide-resistant dihydropteroate synthase Sul3 (144109..143318)
(144823..144578)
hypothetical protein (144823..144578)
(145724..144861)
SDR family NAD(P)-dependent oxidoreductase (145724..144861)
(146659..145955)
IS6 family transposase IS15DIV (146659..145955)
(146810..147625)
aminoglycoside O-phosphotransferase APH(3')-Ia (146810..147625)
(148519..147815)
IS6 family transposase IS15DIV (148519..147815)
(149333..148977)
hypothetical protein (149333..148977)
(150100..149483)
hypothetical protein (150100..149483)
(150294..150728)
peptidase (150294..150728)
umuC (150712..151971)
umuC translesion error-prone DNA polymerase V subunit UmuC (150712..151971)
(152826..152017)
DsbA family protein (152826..152017)
(152933..153544)
hypothetical protein (152933..153544)
(154026..153604)
hypothetical protein (154026..153604)
(154452..154060)
hypothetical protein (154452..154060)
(155226..154477)
thiol:disulfide interchange protein (155226..154477)
(155374..155913)
lytic transglycosylase (155374..155913)
(155996..156382)
hypothetical protein (155996..156382)
(157603..156395)
IS4-like element ISVsa5 family transposase (157603..156395)
(157655..157900)
hypothetical protein (157655..157900)
(159297..158008)
HNH endonuclease (159297..158008)
(163431..159478)
conjugal transfer protein TraG (163431..159478)
(164855..163440)
conjugal transfer protein (164855..163440)
(165891..164845)
thioredoxin family protein (165891..164845)
(166997..166485)
hypothetical protein (166997..166485)
(167799..166999)
trhR (167799..166999)
(168558..169043)
plasmid transfer protein (168558..169043)
(169040..169777)
hypothetical protein (169040..169777)
(169787..172933)
helicase (169787..172933)
(172933..175017)
hypothetical protein (172933..175017)
(175017..176126)
hypothetical protein (175017..176126)
(176113..176775)
DUF4400 domain-containing protein (176113..176775)
(176786..177967)
S49 family peptidase (176786..177967)
(177969..178700)
NERD domain-containing protein (177969..178700)
(179340..178987)
hypothetical protein (179340..178987)
(179690..179406)
hypothetical protein (179690..179406)
(180349..180047)
hypothetical protein (180349..180047)
(181150..180782)
hypothetical protein (181150..180782)
(181851..181315)
hypothetical protein (181851..181315)
(182356..181919)
hypothetical protein (182356..181919)
(182697..182401)
hypothetical protein (182697..182401)
(183024..182818)
hypothetical protein (183024..182818)
(183562..183281)
hypothetical protein (183562..183281)
(184812..183628)
DNA-binding protein (184812..183628)
(185458..185228)
hypothetical protein (185458..185228)
(185914..186858)
hypothetical protein (185914..186858)
(186958..187557)
hypothetical protein (186958..187557)
(187617..187967)
hypothetical protein (187617..187967)
(188013..188216)
hypothetical protein (188013..188216)
(189906..188794)
IS4-like element IS421 family transposase (189906..188794)
(190143..189985)
Hok/Gef family protein (190143..189985)
(191611..190242)
IS3 family transposase (191611..191131)
(192549..191944)
hypothetical protein (192549..191944)
(193046..192765)
hypothetical protein (193046..192765)
(193732..193421)
hypothetical protein (193732..193421)
(194155..193955)
hypothetical protein (194155..193955)
(194419..194195)
hypothetical protein (194419..194195)
(194677..194474)
hypothetical protein (194677..194474)
(195150..194857)
hypothetical protein (195150..194857)
(195721..195230)
DUF3085 domain-containing protein (195721..195230)
(196037..195726)
DUF957 domain-containing protein (196037..195726)
(196456..196193)
hypothetical protein (196456..196193)
(196873..196553)
hypothetical protein (196873..196553)
(197280..197053)
hypothetical protein (197280..197053)
(198119..197508)
hypothetical protein (198119..197508)
(198764..198231)
HNH endonuclease (198764..198231)
(199013..198825)
hypothetical protein (199013..198825)
(199321..199010)
hypothetical protein (199321..199010)
(199623..199384)
hypothetical protein (199623..199384)
(202257..199873)
phosphoadenosine phosphosulfate reductase (202257..199873)
(202879..202430)
hypothetical protein (202879..202430)
(203722..202931)
hypothetical protein (203722..202931)
(204206..203949)
hypothetical protein (204206..203949)
(204598..204272)
hypothetical protein (204598..204272)
(206681..205441)
site-specific DNA-methyltransferase (206681..205441)
(207458..206850)
hypothetical protein (207458..206850)
(207871..207614)
hypothetical protein (207871..207614)
(208364..207936)
hypothetical protein (208364..207936)
(208836..208459)
hypothetical protein (208836..208459)
(210425..209244)
flavin reductase (210425..209244)
(210730..210434)
toxin-plasmid maintenance system killer protein (210730..210434)
(211250..210780)
hypothetical protein (211250..210780)
(214102..211685)
DUF4165 domain-containing protein (214102..211685)
(214636..215400)
hypothetical protein (214636..215400)
(215481..216242)
SAM-dependent methyltransferase (215481..216242)
(216336..216599)
hypothetical protein (216336..216599)
(216620..217231)
hypothetical protein (216620..217231)
(217696..220116)
DUF4165 domain-containing protein (217696..220116)
(221717..221142)
hypothetical protein (221717..221142)
(223169..222114)
RepB family plasmid replication initiator protein (223169..222114)
(226766..224310)
DUF4165 domain-containing protein (226766..224310)
(227250..227164)
PapC protein (227250..227164)
(227216..228489)
IS3 family transposase (227216..227576)
(228505..229101)
hypothetical protein (228505..229101)
(229440..229159)
hypothetical protein (229440..229159)
(229882..229421)
hypothetical protein (229882..229421)
(231795..230104)
DUF4942 domain-containing protein (231795..230104)
(233206..232043)
DNA-binding protein (233206..232043)
(233576..234388)
Dam family site-specific DNA-(adenine-N6)-methyltransferase (233576..234388)
(235251..234397)
hypothetical protein (235251..234397)
(236202..235486)
hypothetical protein (236202..235486)
(236387..236199)
hypothetical protein (236387..236199)
(237374..236400)
IS30-like element ISApl1 family transposase (237374..236400)
(238544..237489)
hypothetical protein (238544..237489)