INTEGRALL

The Integron Database

Klebsiella pneumoniae
Accession Number: CP034325
Source: blood - China
Journal: Unpublished
Published: 12-DEC-2018
Title: Serotype K25 carbapenem-resistant Klebsiella pneumoniae carrying blaNDM-1 and blaKPC-2
Authors: Zhou,Y., Liu,Y.
Remarks: Class 1 integron. In1021
Promoter: PcW
Gene Product Sequence
(156834..156910)
ISKra4 family transposase (156834..156910)
(699..1127)
recombinase family protein (699..1127)
(2102..1446)
quinolone resistance pentapeptide repeat protein QnrS1 (2102..1446)
(3775..2384)
ISKra4-like element ISKpn19 family transposase (3775..2384)
(4384..3812)
recombinase family protein (4384..3812)
(5111..4521)
plasmid pRiA4b ORF-3 family protein (5111..4521)
(5162..5737)
DUF4113 domain-containing protein (5162..5737)
(6165..5884)
XRE family transcriptional regulator (6165..5884)
(6475..6146)
type II toxin-antitoxin system RelE/ParE family toxin (6475..6146)
(6711..6968)
hypothetical protein (6711..6968)
(7417..7112)
hypothetical protein (7417..7112)
(7889..7479)
DUF1380 domain-containing protein (7889..7479)
(8195..7974)
antirestriction protein (8195..7974)
(8738..8508)
hypothetical protein (8738..8508)
(9174..8836)
hypothetical protein (9174..8836)
(10224..9364)
DUF4942 domain-containing protein (10224..9364)
(10476..10297)
cobalamin biosynthesis protein CbiX (10476..10297)
(12366..11083)
DGQHR domain-containing protein (12366..11083)
(12696..12430)
XRE family transcriptional regulator (12696..12430)
(13190..12741)
DNA repair protein RadC (13190..12741)
(13674..13312)
DUF3085 domain-containing protein (13674..13312)
(13959..13696)
hypothetical protein (13959..13696)
(14487..14077)
hypothetical protein (14487..14077)
(14995..14516)
hypothetical protein (14995..14516)
(15233..14988)
sugar ABC transporter substrate-binding protein (15233..14988)
(16163..15612)
phospholipase D family protein (16163..15612)
(16616..16173)
plasmid stability family protein (16616..16173)
(17593..16619)
recombinase (17593..16619)
(18574..17834)
phage integrase family protein (18574..17834)
(18841..18593)
hypothetical protein (18841..18593)
(19323..18838)
hypothetical protein (19323..18838)
(19907..19320)
restriction endonuclease (19907..19320)
(20148..19900)
XRE family transcriptional regulator (20148..19900)
(20606..20145)
hypothetical protein (20606..20145)
(20741..21286)
hypothetical protein (20741..21286)
(21846..21439)
hypothetical protein (21846..21439)
(22426..21848)
hypothetical protein (22426..21848)
(22760..22404)
hypothetical protein (22760..22404)
(23289..24620)
RelB antitoxin (23289..24620)
(24637..25338)
hypothetical protein (24637..25338)
(25383..25601)
hypothetical protein (25383..25601)
(25604..25813)
hypothetical protein (25604..25813)
(26280..26519)
hypothetical protein (26280..26519)
(26664..26984)
chromosome segregation protein ParM (26664..26984)
(26987..27835)
3'-5' exonuclease (26987..27835)
umuC (29162..27858)
umuC translesion error-prone DNA polymerase V subunit UmuC (29162..27858)
(29545..29111)
translesion error-prone DNA polymerase V autoproteolytic subunit (29545..29111)
(29970..29638)
mRNA interferase PemK (29970..29638)
(30229..29972)
antitoxin (30229..29972)
(30975..30322)
CPBP family intramembrane metalloprotease (30975..30322)
(31055..31438)
DUF1496 domain-containing protein (31055..31438)
(31543..31938)
lytic transglycosylase (31543..31938)
(31983..33245)
conjugal transfer protein TrbA (31983..33245)
(33256..34218)
DsbC family protein (33256..34218)
(34231..36318)
conjugal transfer protein TrbC (34231..36318)
(38755..37688)
replication protein RepA (38755..37688)
(39270..39040)
RepC (39270..39040)
(39997..39344)
ExcA (39997..39344)
(42180..40000)
type IV secretion protein DotA (42180..40000)
(42823..42173)
TraX-like protein (42823..42173)
(44028..42820)
hypothetical protein (44028..42820)
(47075..44025)
conjugal transfer protein (47075..44025)
(47566..47072)
hypothetical protein (47566..47072)
(48001..47612)
conjugal transfer protein (48001..47612)
(48548..48018)
hypothetical protein (48548..48018)
(49276..48572)
TraP (49276..48572)
(50637..49288)
TraO (50637..49288)
(51800..50649)
hypothetical protein (51800..50649)
(52591..51809)
conjugal transfer protein (52591..51809)
(52590..53000)
hypothetical protein (52590..53000)
(52987..53184)
hypothetical protein (52987..53184)
(53697..53185)
hypothetical protein (53697..53185)
(55342..53663)
hypothetical protein (55342..53663)
(57118..56858)
TraK (57118..56858)
traJ (58271..57108)
traJ plasmid transfer ATPase TraJ (58271..57108)
(59061..58282)
conjugal transfer protein (59061..58282)
(59558..59058)
TraH (59558..59058)
(61551..59572)
hypothetical protein (61551..59572)
(61855..61538)
NikA (61855..61538)
(62130..62495)
MobC (62130..62495)
(63533..62997)
hypothetical protein (63533..62997)
(63977..63666)
hypothetical protein (63977..63666)
ssb (64467..64033)
ssb single-stranded DNA-binding protein (64467..64033)
(64760..64539)
hypothetical protein (64760..64539)
(65199..64915)
hypothetical protein (65199..64915)
(65683..65243)
antirestriction protein (65683..65243)
(65764..65907)
transposase (65764..65907)
(66456..66043)
helix-turn-helix domain-containing protein (66456..66043)
(66735..66457)
XRE family transcriptional regulator (66735..66457)
(67045..66725)
type II toxin-antitoxin system RelE/ParE family toxin (67045..66725)
(67350..67126)
hypothetical protein (67350..67126)
(67573..67361)
hypothetical protein (67573..67361)
(67990..67634)
hypothetical protein (67990..67634)
(68112..67987)
single-stranded DNA-binding protein (68112..67987)
(68165..68434)
hypothetical protein (68165..68434)
(69149..68832)
hypothetical protein (69149..68832)
(69514..69164)
hypothetical protein (69514..69164)
(69783..69511)
hypothetical protein (69783..69511)
(70166..69831)
hypothetical protein (70166..69831)
(70634..70476)
type I toxin-antitoxin system Hok family toxin (70634..70476)
(70691..70801)
protein sok (70691..70801)
(71236..70862)
hypothetical protein (71236..70862)
(71618..71292)
theronine dehydrogenase (71618..71292)
(72343..71615)
plasmid SOS inhibition protein A (72343..71615)
psiB (72771..72340)
psiB conjugation system SOS inhibitor PsiB (72771..72340)
(74873..72816)
ParB/RepB/Spo0J family partition protein (74873..72816)
(75191..74943)
DUF905 domain-containing protein (75191..74943)
ssb (75782..75240)
ssb single-stranded DNA-binding protein (75782..75240)
(75993..76313)
hypothetical protein (75993..76313)
(76771..76208)
class I SAM-dependent methyltransferase (76771..76208)
(78174..76819)
DUF3560 domain-containing protein (78174..76819)
(78456..78226)
hypothetical protein (78456..78226)
(78775..78548)
hypothetical protein (78775..78548)
(79350..79246)
DNA polymerase III subunit theta (79350..79246)
(79702..79382)
hypothetical protein (79702..79382)
(79991..79737)
DNA polymerase III subunit theta (79991..79737)
(80369..80010)
hypothetical protein (80369..80010)
(80918..80412)
antirestriction protein ArdA (80918..80412)
(81389..80961)
antirestriction protein (81389..80961)
(82837..82070)
hypothetical protein (82837..82070)
(83310..82891)
DUF1380 domain-containing protein (83310..82891)
(83541..83320)
hypothetical protein (83541..83320)
(84242..83541)
DNA methylase (84242..83541)
(84909..84679)
hypothetical protein (84909..84679)
(85644..84973)
Mediator of plasmid stability (85644..84973)
(86618..85647)
StbA family protein (86618..85647)
ltrA (88351..86867)
ltrA group II intron reverse transcriptase/maturase (88351..86867)
(88602..88351)
hypothetical protein (88602..88351)
(88761..89192)
translesion error-prone DNA polymerase V autoproteolytic subunit (88761..89192)
umuC (89192..90463)
umuC translesion error-prone DNA polymerase V subunit UmuC (89192..90463)
(90875..91750)
RepB family plasmid replication initiator protein (90875..91750)
(92423..93049)
cobyrinic acid ac-diamide synthase (92423..93049)
(93169..93348)
Par-like protein (93169..93348)
(94646..93852)
phage integrase family protein (94646..93852)
(95860..94844)
hypothetical protein (95860..94844)
(96185..95871)
hypothetical protein (96185..95871)
(96571..96212)
hypothetical protein (96571..96212)
ccdB (97081..96776)
ccdB type II toxin-antitoxin system toxin CcdB (97081..96776)
ccdA (97301..97083)
ccdA type II toxin-antitoxin system antitoxin CcdA (97301..97083)
(97353..97547)
hypothetical protein (97353..97547)
(97809..97471)
hypothetical protein (97809..97471)
(97932..98129)
hypothetical protein (97932..98129)
(98409..98119)
korC (98409..98119)
(99533..98406)
DUF4238 domain-containing protein (99533..98406)
(101159..99567)
hypothetical protein (101159..99567)
(102145..101366)
hypothetical protein (102145..101366)
(102658..102158)
hypothetical protein (102658..102158)
(102933..103196)
hypothetical protein (102933..103196)
(103193..103759)
hypothetical protein (103193..103759)
(103790..104284)
DNA-binding protein (103790..104284)
(104328..104696)
hypothetical protein (104328..104696)
(104730..104933)
hemolysin expression modulator Hha (104730..104933)
(104982..105239)
hypothetical protein (104982..105239)
(105315..105569)
hypothetical protein (105315..105569)
(106481..105705)
DUF2971 domain-containing protein (106481..105705)
(107045..106722)
hypothetical protein (107045..106722)
(107493..107224)
SOS response-associated peptidase (107493..107224)
(107583..107494)
PTS fructose IIA subunit (107583..107494)
(107629..107796)
IS5/IS1182 family transposase (107629..107796)
(107852..108001)
IS110 family transposase (107852..108001)
(108284..109465)
DUF4268 domain-containing protein (108284..109465)
(109829..110041)
hypothetical protein (109829..110041)
(110163..110351)
hypothetical protein (110163..110351)
repA (111514..110657)
repA incFII family plasmid replication initiator RepA (111514..110657)
tap (111584..111507)
tap RepA leader peptide Tap (111584..111507)
repA (112067..111816)
repA replication regulatory protein RepA (112067..111816)
(112712..112203)
phospholipase D family protein (112712..112203)
(114463..112886)
PAS domain S-box protein (114463..112886)
(114787..115491)
IS6-like element IS26 family transposase (114787..115491)
(115556..115437)
5,10-methylenetetrahydrofolate reductase (115556..115437)
(115541..116260)
hypothetical protein (115541..116260)
(116247..117098)
replication protein C (116247..117098)
(117382..117305)
transcriptional regulator (117382..117305)
sul2 (117403..118218)
sul2 sulfonamide-resistant dihydropteroate synthase Sul2 (117403..118218)
aph(3'')-Ib (118279..119082)
aph(3'')-Ib aminoglycoside O-phosphotransferase APH(3'')-Ib (118279..119082)
(119082..119918)
aminoglycoside O-phosphotransferase APH(6)-Id (119082..119918)
(120683..119979)
IS6-like element IS26 family transposase (120683..119979)
(120834..121649)
aminoglycoside O-phosphotransferase APH(3')-Ia (120834..121649)
(122543..121839)
IS6-like element IS26 family transposase (122543..121839)
(122776..123636)
aminoglycoside N-acetyltransferase AAC(3)-IId (122776..123636)
(123649..123888)
tunicamycin resistance protein (123649..123888)
(124005..124358)
IS6 family transposase (124005..124358)
(124423..125127)
IS6-like element IS26 family transposase (124423..125127)
(125629..125345)
transposase (125629..125345)
(126611..125598)
class 1 integron integrase IntI1 (126611..125598)
(126903..127457)
fluoroquinolone-acetylating aminoglycoside 6'-N-acetyltransferase AAC(6')-Ib-cr5 (126903..127457)
(127554..128006)
NAD(+)--rifampin ADP-ribosyltransferase Arr-3 (127554..128006)
(128139..128612)
trimethoprim-resistant dihydrofolate reductase DfrA27 (128139..128612)
(128793..129638)
ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA16 (128793..129638)
(129755..130102)
quaternary ammonium compound efflux SMR transporter QacE delta 1 (129755..130102)
sul1 (130096..130935)
sul1 sulfonamide-resistant dihydropteroate synthase Sul1 (130096..130935)
(131340..132881)
IS91 family transposase (131340..132881)
(133653..133114)
peptide ABC transporter substrate-binding protein SapA (133653..133114)
(134188..134640)
SgcJ/EcaC family oxidoreductase (134188..134640)
(135326..134682)
quinolone resistance pentapeptide repeat protein QnrB91 (135326..134682)
pspF (135628..135422)
pspF phage shock protein operon transcriptional activator (135628..135422)
(135620..135823)
QacE family quaternary ammonium compound efflux SMR transporter (135620..135823)
sul1 (135817..136656)
sul1 sulfonamide-resistant dihydropteroate synthase Sul1 (135817..136656)
(136765..136586)
hypothetical protein (136765..136586)
(136784..137284)
GNAT family N-acetyltransferase (136784..137284)
(137703..137590)
NTP-binding protein (137703..137590)
(137791..138555)
IS6-like element IS6100 family transposase (137791..138555)
(138616..138527)
type VII secretion-associated protein (138616..138527)
(139102..138746)
hypothetical protein (139102..138746)
(139632..139048)
TetR/AcrR family transcriptional regulator (139632..139048)
(140870..139632)
MFS transporter (140870..139632)
mph(A) (141772..140867)
mph(A) Mph(A) family macrolide 2'-phosphotransferase (141772..140867)
(141835..141948)
adenine-specific DNA-methyltransferase (141835..141948)
(142598..141894)
IS6-like element IS26 family transposase (142598..141894)
(142663..142917)
hypothetical protein (142663..142917)
(142975..143217)
relaxase (142975..143217)
(143926..143249)
TetR family transcriptional regulator (143926..143249)
tet(A) (144005..145204)
tet(A) tetracycline efflux MFS transporter Tet(A) (144005..145204)
(145359..145171)
IS91 family transposase (145359..145171)
(145776..145471)
LysR family transcriptional regulator (145776..145471)
floR (147018..145804)
floR chloramphenicol/florfenicol efflux MFS transporter FloR (147018..145804)
(147963..147235)
DUF3363 domain-containing protein (147963..147235)
(150970..147965)
Tn3-like element Tn3 family transposase (150970..147965)
(151134..151691)
recombinase family protein (151134..151691)
(151874..152734)
class A broad-spectrum beta-lactamase TEM-1 (151874..152734)
(152993..153469)
cupin fold metalloprotein, WbuC family (152993..153469)
(154391..153516)
class A extended-spectrum beta-lactamase CTX-M-3 (154391..153516)
(154920..154726)
IS1380 family transposase (154920..154726)
(154977..155674)
IS1 family transposase (154977..155674)
(156595..155690)
IS1380 family transposase (156595..155690)